1iyg: Difference between revisions
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<StructureSection load='1iyg' size='340' side='right'caption='[[1iyg]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1iyg' size='340' side='right'caption='[[1iyg]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1iyg]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1iyg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IYG FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iyg OCA], [https://pdbe.org/1iyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iyg RCSB], [https://www.ebi.ac.uk/pdbsum/1iyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iyg ProSAT], [https://www.topsan.org/Proteins/RSGI/1iyg TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/FIS1_MOUSE FIS1_MOUSE]] Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 14:07, 4 August 2021
Solution structure of RSGI RUH-001, a Fis1p-like and CGI-135 homologous domain from a mouse cDNASolution structure of RSGI RUH-001, a Fis1p-like and CGI-135 homologous domain from a mouse cDNA
Structural highlights
Function[FIS1_MOUSE] Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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