Growth factors: Difference between revisions
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**[[IGF1]] | **[[IGF1]] | ||
*[[Interleukin]] | *[[Interleukin]] | ||
'''Interleukin''' (IL) is a cytokine which functions in the immune system. IL families are denoted by numbers<ref>PMID:3277884</ref>.<br /> | |||
'''IL-1''' is a group of 11 cytokines which regulate immune and inflammatory response. See [[Interleukin-1 beta]].<br /> | |||
'''IL-2''' is a cytokine made by leukocytes. It is used in cancer therapy to boost the immune system.<br /> | |||
'''IL-3''' improves the body's natural response to disease by stimulating the differentiation of multipotent hematopoietic stem cells into myeloid or lymphoid progenitor cells.<br /> | |||
'''IL-4''' induces the differentiation of naive helper T cells (Th0) to Th2 cells.<br /> | |||
'''IL-5''' stimulates B cell growth and increases immunoglobulin secretion.<br /> | |||
'''IL-6''' is both a pro-inflammatory cytokine and anti-inflammatory myokine.<br /> | |||
'''IL-7''' is a cytokine important for B and T cells development.<br /> | |||
'''IL-8''' induces chemotaxis and phagocytosis.<br /> | |||
'''IL-10''' see [[Interleukin-10]] and [[Inflammation & Rheumatoid Arthritis]].<br /> | |||
'''IL-11''' involved in the stimulation of megakaryocyte maturation.<br /> | |||
''' IL-12''' induces the differentiation of naive helper T cells (Th0) to Th1 cells. See [[Interleukin-12]].<br /> | |||
'''IL-13''' induces the differentiation of naive helper T cells (Th0) to Th2 cells.<br /> | |||
'''IL-15''' see [[Interleukin-15]].<br /> | |||
'''IL-16''' acts as chemoattractant, modulator of T cell activity and inhibitor of HIV replication.<br /> | |||
'''IL-17''' recruits monocytes and neutrophils to the site of inflammation.<br /> | |||
'''IL-18''' induces cell-mediated immunity following infection by microbial lipopolysaccharides.<br /> | |||
'''IL-19''' induces activation of the signal transducer and activator of STAT3.<br /> | |||
''' IL-21''' has potent effect on natural killer cells.<br /> | |||
'''IL-22''' stimulates inflammatory responses like S100 and defensin.<br /> | |||
''' IL-23''' induces activation of the signal transducer and activator of STAT4.<br /> | |||
''' IL-24''' induces activation of the signal transducer and activator of STAT1 and STAT3.<br /> | |||
'''IL-28''' has a role in the immune defense against viruses.<br /> | |||
'''IL-29''' similar to IL-28.<br /> | |||
'''IL-33''' induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines.<br /> | |||
'''IL-34''' increases growth or survival of monocytes.<br /> | |||
'''IL-36''' acts on naïve CD4+ T cells.<br /> | |||
''' IL-37''' has a role in inhibiting both innate and adaptive immune responses.<br /> | |||
*[[Neurotrophin]] | *[[Neurotrophin]] | ||
**[[High affinity nerve growth factor receptor]] | **[[High affinity nerve growth factor receptor]] | ||