Bone morphogenetic protein: Difference between revisions
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== Function == | == Function == | ||
'''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. | '''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. See also [[Growth factors]] and [[Growth differentiation factor]]. | ||
== Relevance == | == Relevance == |
Revision as of 16:47, 1 August 2021
FunctionBone morphogenetic protein (BMP) are growth factors which can induce formation of bone and cartllage'[1]. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see Student Projects for UMass Chemistry 423 Spring 2012-4. See also Growth factors and Growth differentiation factor. RelevanceRecombinant BMP is used in oral surgery and spinal fusion. DiseaseBMP-7 is involved in chronic kidney disease[2]. 3D structures of bone morphogenetic proteinBone morphogenetic protein 3D structures
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ReferencesReferences
- ↑ Reddi AH, Reddi A. Bone morphogenetic proteins (BMPs): from morphogens to metabologens. Cytokine Growth Factor Rev. 2009 Oct-Dec;20(5-6):341-2. doi:, 10.1016/j.cytogfr.2009.10.015. Epub 2009 Nov 8. PMID:19900831 doi:http://dx.doi.org/10.1016/j.cytogfr.2009.10.015
- ↑ Mitu G, Hirschberg R. Bone morphogenetic protein-7 (BMP7) in chronic kidney disease. Front Biosci. 2008 May 1;13:4726-39. PMID:18508541