1f29: Difference between revisions

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<StructureSection load='1f29' size='340' side='right'caption='[[1f29]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='1f29' size='340' side='right'caption='[[1f29]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1f29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1F29 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1f29]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F29 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VS1:3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5-+PHENYL-PENTANE-1-SULFONYLBENZENE'>VS1</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VS1:3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5-+PHENYL-PENTANE-1-SULFONYLBENZENE'>VS1</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f2a|1f2a]], [[1f2b|1f2b]], [[1f2c|1f2c]], [[1aim|1aim]], [[2aim|2aim]], [[1ewl|1ewl]], [[1ewm|1ewm]], [[1ewo|1ewo]], [[1ewp|1ewp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1f2a|1f2a]], [[1f2b|1f2b]], [[1f2c|1f2c]], [[1aim|1aim]], [[2aim|2aim]], [[1ewl|1ewl]], [[1ewm|1ewm]], [[1ewo|1ewo]], [[1ewp|1ewp]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f29 OCA], [http://pdbe.org/1f29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1f29 RCSB], [http://www.ebi.ac.uk/pdbsum/1f29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1f29 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f29 OCA], [https://pdbe.org/1f29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f29 RCSB], [https://www.ebi.ac.uk/pdbsum/1f29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f29 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.  The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.  
[[https://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.  The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

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