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==Crystal structure of IspD from Mycobacterium paratuberculosis== | ==Crystal structure of IspD from Mycobacterium paratuberculosis== | ||
<StructureSection load='7kmw' size='340' side='right'caption='[[7kmw]]' scene=''> | <StructureSection load='7kmw' size='340' side='right'caption='[[7kmw]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KMW OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[7kmw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycpa Mycpa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KMW FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, MAP_0476 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=262316 MYCPA])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmw OCA], [https://pdbe.org/7kmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kmw RCSB], [https://www.ebi.ac.uk/pdbsum/7kmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmw ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/ISPD_MYCPA ISPD_MYCPA]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycpa]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: | [[Category: Cytidylyltransferase]] | ||
[[Category: | [[Category: Ispd]] | ||
[[Category: | [[Category: Ssgcid]] | ||
[[Category: | [[Category: Transferase]] | ||
Revision as of 12:15, 21 July 2021
Crystal structure of IspD from Mycobacterium paratuberculosisCrystal structure of IspD from Mycobacterium paratuberculosis
Structural highlights
Function[ISPD_MYCPA] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). |
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