Ets1: Difference between revisions
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<StructureSection load='1mdm' size='340' side='right' caption='Structure of mouse Ets1 ETS domain (green) complex with paired box protein Pax5 (magenta) and MB-1 promoter DNA (PDB code [[1mdm]]).' scene='59/595751/Cv/1'> | <StructureSection load='1mdm' size='340' side='right' caption='Structure of mouse Ets1 ETS domain (green) complex with paired box protein Pax5 (magenta) and MB-1 promoter DNA (PDB code [[1mdm]]).' scene='59/595751/Cv/1'> | ||
== Function == | == Function == | ||
'''Ets1 (E26 Transformation-Specific)''' is a proto-oncogene translation factor. Ets1 contributes to the regulation of cellular differentiation<ref>PMID:17986575</ref> . | '''Ets1 (E26 Transformation-Specific)''' or '''p54''' is a proto-oncogene translation factor. Ets1 contributes to the regulation of cellular differentiation<ref>PMID:17986575</ref> . | ||
== Relevance == | == Relevance == | ||
Ets1 promotes invasive behavior in endothelial cells, smooth muscle cells and epithelial cancer cells. | Ets1 promotes invasive behavior in endothelial cells, smooth muscle cells and epithelial cancer cells. | ||