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==Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog==
==Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog==
<StructureSection load='2ri9' size='340' side='right' caption='[[2ri9]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2ri9' size='340' side='right'caption='[[2ri9]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ri9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_1109 Atcc 1109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RI9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ri9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_1109 Atcc 1109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RI9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LDY:ALPHA-D-LYXOPYRANOSE'>LDY</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LDY:ALPHA-D-LYXOPYRANOSE'>LDY</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kkt|1kkt]], [[1kre|1kre]], [[1krf|1krf]], [[2ri8|2ri8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kkt|1kkt]], [[1kre|1kre]], [[1krf|1krf]], [[2ri8|2ri8]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSDC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5077 ATCC 1109])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSDC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5077 ATCC 1109])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,2-alpha-mannosidase Mannosyl-oligosaccharide 1,2-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.113 3.2.1.113] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,2-alpha-mannosidase Mannosyl-oligosaccharide 1,2-alpha-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.113 3.2.1.113] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ri9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ri9 OCA], [http://pdbe.org/2ri9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ri9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ri9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ri9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ri9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ri9 OCA], [https://pdbe.org/2ri9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ri9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ri9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ri9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MAN12_PENCI MAN12_PENCI]] Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).  
[[https://www.uniprot.org/uniprot/MAN12_PENCI MAN12_PENCI]] Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Mannosidase|Mannosidase]]
*[[Mannosidase 3D structures|Mannosidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Atcc 1109]]
[[Category: Atcc 1109]]
[[Category: Large Structures]]
[[Category: Mannosyl-oligosaccharide 1,2-alpha-mannosidase]]
[[Category: Mannosyl-oligosaccharide 1,2-alpha-mannosidase]]
[[Category: Claeyssens, M]]
[[Category: Claeyssens, M]]

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