Cyclin 3D structures: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*CYCA | |||
**[[7b5l]] – hCYCA + CDK2 + NEDD8 + cullin-1 + RBX1 + SKP1 + SKP2 + CKSHS1 + p27 + UBE2L3 + Ub + ARIH1 – human - Cryo EM<br /> | |||
*CYCA2 | *CYCA2 | ||
**[[3my5]], [[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[3dog]], [[3ddp]], [[3ddq]], [[3bht]], [[2v22]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[2bpm]], [[2c4g]], [[1fvv]], [[2c6t]] – hCYCA2 +CDK2+inhibitor | **[[3my5]], [[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[3dog]], [[3ddp]], [[3ddq]], [[3bht]], [[2v22]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[2bpm]], [[2c4g]], [[1fvv]], [[2c6t]] – hCYCA2 +CDK2+inhibitor <br /> | ||
**[[3bhu]], [[3bhv]], [[2uzd]], [[2uzb]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2iw6]], [[2iw8]], [[2iw9]], [[2g9x]], [[1oi9]], [[1oiu]], [[1oiy]], [[1ogu]], [[1p5e]], [[1pkd]], [[1h1p]], [[1h1q]], [[1h1r]], [[1h1s]], [[4cfx]], [[4cfv]], [[4cfu]], [[4cfm]], [[5nev]], [[5nev]], [[5lmk]], [[5cyi]] - hCYCA2 +CDK2 T160P+inhibitor<br /> | **[[3bhu]], [[3bhv]], [[2uzd]], [[2uzb]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2iw6]], [[2iw8]], [[2iw9]], [[2g9x]], [[1oi9]], [[1oiu]], [[1oiy]], [[1ogu]], [[1p5e]], [[1pkd]], [[1h1p]], [[1h1q]], [[1h1r]], [[1h1s]], [[4cfx]], [[4cfv]], [[4cfu]], [[4cfm]], [[5nev]], [[5nev]], [[5lmk]], [[5cyi]] - hCYCA2 +CDK2 T160P+inhibitor<br /> | ||
**[[1fin]], [[5if1]] - hCYCA2 +CDK2<br /> | **[[1fin]], [[5if1]] - hCYCA2 +CDK2<br /> | ||
**[[1vyw]] - hCYCA2 C-terminal + hCDK2<br /> | **[[1vyw]] - hCYCA2 C-terminal 175-432 + hCDK2<br /> | ||
**[[1jst]], [[3tnw]] - hCYCA2 +CDK2 T160P<br /> | **[[1jst]], [[3tnw]], [[6sg4]] - hCYCA2 +CDK2 T160P<br /> | ||
**[[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]] - hCYCA2 +CDK2 T160P+peptide<br /> | **[[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]] - hCYCA2 +CDK2 T160P+peptide<br /> | ||
**[[4bck]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfn]], [[4cfw]], [[6gva]], [[6guf]], [[6gue]], [[6guc]], [[6gub]] - hCYCA2 +CDK2 T160P + inhibitor<br /> | **[[4bck]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfn]], [[4cfw]], [[6gva]], [[6guf]], [[6gue]], [[6guc]], [[6gub]] - hCYCA2 +CDK2 T160P + inhibitor<br /> | ||
**[[6ath]] - hCYCA2 +CDK2 T160P + cyclin-dependent kinase inhibitor<br /> | **[[6ath]] - hCYCA2 +CDK2 T160P + cyclin-dependent kinase inhibitor<br /> | ||
**[[4fx3]] - hCYCA2 +CDK2 + inhibitor<br /> | **[[4fx3]] - hCYCA2 +CDK2 + inhibitor<br /> | ||
**[[4eoi]], [[4eoj]], [[4eok]], [[4eol]], [[4eom]], [[4eon]], [[4eoo]], [[4eop]], [[4eoq]], [[4eor]], [[4eos]] - hCYCA2 C-terminal +CDK2 T160P + inhibitor<br /> | **[[4eoi]], [[4eoj]], [[4eok]], [[4eol]], [[4eom]], [[4eon]], [[4eoo]], [[4eop]], [[4eoq]], [[4eor]], [[4eos]], [[6rij]], [[7ack]] - hCYCA2 C-terminal +CDK2 T160P + inhibitor<br /> | ||
**[[2cjm]] - hCYCA2 +CDK2 T160P Y15P<br /> | **[[2cjm]] - hCYCA2 +CDK2 T160P Y15P<br /> | ||
**[[2cch]] - hCYCA2 +CDK2 T160P+ATP analog<br /> | **[[2cch]] - hCYCA2 +CDK2 T160P+ATP analog<br /> | ||
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**[[3rgf]], [[4g6l]] – hCYCC + CDK8<br /> | **[[3rgf]], [[4g6l]] – hCYCC + CDK8<br /> | ||
**[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]], [[5idp]], [[5idn]], [[5icp]], [[5i5z]], [[5hvy]], [[5hnb]], [[5hbj]], [[5hbh]], [[5hbe]], [[5fgk]], [[5cei]], [[5bnj]], [[5xqx]], [[5xs2]], [[6qtg]], [[6qtj]], [[6r3s]], [[6t41]] – hCYCC + CDK8 + inhibitor<br /> | **[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]], [[5idp]], [[5idn]], [[5icp]], [[5i5z]], [[5hvy]], [[5hnb]], [[5hbj]], [[5hbh]], [[5hbe]], [[5fgk]], [[5cei]], [[5bnj]], [[5xqx]], [[5xs2]], [[6qtg]], [[6qtj]], [[6r3s]], [[6t41]] – hCYCC + CDK8 + inhibitor<br /> | ||
**[[6tpa]] – hCYCC + CDK8 + drug<br /> | |||
*CYCD | *CYCD | ||
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**[[1kxu]], [[1jkw]] – hCYCH<br /> | **[[1kxu]], [[1jkw]] – hCYCH<br /> | ||
**[[6o9l]] – hCYCH in transcription preinitiation complex – Cryo EM<br /> | **[[6o9l]] – hCYCH in transcription preinitiation complex – Cryo EM<br /> | ||
**[[6xbz]] – hCYCH + CDK7 + MAT1 – Cryo EM<br /> | |||
**[[6xd3]], [[7b5o]], [[7b5q]] – hCYCH + CDK7 + MAT1 + inhibitor – Cryo EM<br /> | |||
*CYCK | *CYCK | ||
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**[[4cxa]] - hCYCK + CDK12 T160P + AMPPNP<br /> | **[[4cxa]] - hCYCK + CDK12 T160P + AMPPNP<br /> | ||
**[[5efq]], [[4nst]] - hCYCK + CDK13 T160P + ADP<br /> | **[[5efq]], [[4nst]] - hCYCK + CDK13 T160P + ADP<br /> | ||
**[[4un0]], [[5acb]], [[6b3e]], [[6ckx]] - hCYCK +CDK12 T160P + inhibitor<br /> | **[[4un0]], [[5acb]], [[6b3e]], [[6ckx]], [[7nxj]], [[7nxk]] - hCYCK +CDK12 T160P + inhibitor<br /> | ||
**[[6td3]] - hCYCK +CDK12 T160P+ DDB1<br /> | **[[6td3]] - hCYCK +CDK12 T160P+ DDB1<br /> | ||
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**[[3lq5]], [[3tn8]], [[3tnh]], [[3tni]], [[4bcf]], [[4bcg]], [[4bch]], [[4bci]], [[4bcj]] – hCYCT1 (mutant)+CDK9<br /> | **[[3lq5]], [[3tn8]], [[3tnh]], [[3tni]], [[4bcf]], [[4bcg]], [[4bch]], [[4bci]], [[4bcj]] – hCYCT1 (mutant)+CDK9<br /> | ||
**[[3blr]] - hCYCT1 +CDK9+inhibitor<br /> | **[[3blr]] - hCYCT1 +CDK9+inhibitor<br /> | ||
**[[6gzh]] - hCYCT1 TPO160 +CDK9+inhibitor<br /> | **[[6gzh]], [[6z45]] - hCYCT1 TPO160 +CDK9+inhibitor<br /> | ||
**[[3my1]], [[4ec8]], [[4ec9]] - hCYCT1 (mutant)+CDK9 TPO160 +inhibitor<br /> | **[[3my1]], [[4ec8]], [[4ec9]] - hCYCT1 (mutant)+CDK9 TPO160 +inhibitor<br /> | ||
**[[3mi9]], [[3mia]] - hCYCT1 +CDK9+protein TAT<br /> | **[[3mi9]], [[3mia]] - hCYCT1 +CDK9+protein TAT<br /> | ||