6lbd: Difference between revisions
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==shrimp ferritin T158R G159R== | ==shrimp ferritin T158R G159R== | ||
<StructureSection load='6lbd' size='340' side='right'caption='[[6lbd]]' scene=''> | <StructureSection load='6lbd' size='340' side='right'caption='[[6lbd]], [[Resolution|resolution]] 1.39Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LBD OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6lbd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Kuruma_prawn Kuruma prawn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LBD FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lbd OCA], [https://pdbe.org/6lbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lbd RCSB], [https://www.ebi.ac.uk/pdbsum/6lbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lbd ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/T2B7E1_PENJP T2B7E1_PENJP]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.[RuleBase:RU361145] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Protein colloid crystals are considered as high porous soft materials, presenting great potentials in nutrients and drug encapsulation, but protein crystal fabrication usually needs precipitant and high protein concentration. Herein, an easy implemented approach was reported for the construction of protein colloid crystals in diluted solution with shimp ferritin as building blocks by taking advantage of the strength of multiple intermolecular arginine-arginine interactions. The X-ray single-crystal structure reveals that a group of exquisite arginine-arginine interactions between two neighboring ferritin enable them self-assembly into long-range ordered protein soft materials. The arginine-arginine interactions mediate crystal generation favored at pH 9.5 with 200 mM NaCl, and the resulting colloid crystals exhibit high thermal stability (90 degrees C for 30 min). Importantly, the interglobular cavity in colloid crystals is three times larger in volume than that of intrinsic ferritin cavity in each unit cell, which can be used for molecular encapsulation. | |||
Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions.,Chen H, Zhang T, Tan X, Wang Y, Liu Y, Zhao G Food Chem. 2021 Jul 1;349:129089. doi: 10.1016/j.foodchem.2021.129089. Epub 2021 , Jan 19. PMID:33548881<ref>PMID:33548881</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 6lbd" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Ferroxidase]] | |||
[[Category: Kuruma prawn]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen H]] | [[Category: Chen, H]] | ||
[[Category: Zhao G]] | [[Category: Zhao, G]] | ||
[[Category: Ferritin]] | |||
[[Category: Iron]] | |||
[[Category: Metal binding protein]] | |||