2mtf: Difference between revisions

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==Solution structure of the La motif of human LARP6==
==Solution structure of the La motif of human LARP6==
<StructureSection load='2mtf' size='340' side='right' caption='[[2mtf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mtf' size='340' side='right'caption='[[2mtf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LARP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LARP6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [http://pdbe.org/2mtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [http://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN]] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>   
[[https://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN]] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Atkinson, A R]]
[[Category: Atkinson, A R]]
[[Category: Conte, M R]]
[[Category: Conte, M R]]

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