2mo5: Difference between revisions

<StructureSection load='2mo5' size='340' side='right' caption='[[2mo5]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[2mo5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MO5 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP2, FABPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mo5 OCA], [http://pdbe.org/2mo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mo5 RCSB], [http://www.ebi.ac.uk/pdbsum/2mo5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mo5 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/FABPI_HUMAN FABPI_HUMAN]] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.  

*[[Fatty acid-binding protein|Fatty acid-binding protein]]