1e3q: Difference between revisions
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==TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51== | ==TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51== | ||
<StructureSection load='1e3q' size='340' side='right' caption='[[1e3q]], [[Resolution|resolution]] 2.85Å' scene=''> | <StructureSection load='1e3q' size='340' side='right'caption='[[1e3q]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1e3q]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1e3q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E3Q FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EBW:4-(5-{4-[DIMETHYL(PROP-2-ENYL)AMMONIO]PHENYL}-3-OXOPENTYL)-N,N-DIMETHYL-N-PROP-2-ENYLBENZENAMINIUM'>EBW</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EBW:4-(5-{4-[DIMETHYL(PROP-2-ENYL)AMMONIO]PHENYL}-3-OXOPENTYL)-N,N-DIMETHYL-N-PROP-2-ENYLBENZENAMINIUM'>EBW</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ace|2ace]], [[3ace|3ace]], [[4ace|4ace]], [[1acj|1acj]], [[2ack|2ack]], [[1acl|1acl]], [[1amn|1amn]], [[1fss|1fss]], [[1vot|1vot]], [[1ax9|1ax9]], [[1eve|1eve]], [[1cfj|1cfj]], [[1oce|1oce]], [[2dfp|2dfp]], [[1som|1som]], [[2dx6|2dx6]], [[1vxo|1vxo]], [[1vxr|1vxr]], [[1qti|1qti]], [[1qig|1qig]], [[1qih|1qih]], [[1qii|1qii]], [[1qij|1qij]], [[1qik|1qik]], [[1qim|1qim]], [[1qid|1qid]], [[1qie|1qie]], [[1qif|1qif]], [[1eea|1eea]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ace|2ace]], [[3ace|3ace]], [[4ace|4ace]], [[1acj|1acj]], [[2ack|2ack]], [[1acl|1acl]], [[1amn|1amn]], [[1fss|1fss]], [[1vot|1vot]], [[1ax9|1ax9]], [[1eve|1eve]], [[1cfj|1cfj]], [[1oce|1oce]], [[2dfp|2dfp]], [[1som|1som]], [[2dx6|2dx6]], [[1vxo|1vxo]], [[1vxr|1vxr]], [[1qti|1qti]], [[1qig|1qig]], [[1qih|1qih]], [[1qii|1qii]], [[1qij|1qij]], [[1qik|1qik]], [[1qim|1qim]], [[1qid|1qid]], [[1qie|1qie]], [[1qif|1qif]], [[1eea|1eea]]</div></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3q OCA], [https://pdbe.org/1e3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3q RCSB], [https://www.ebi.ac.uk/pdbsum/1e3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/1e3q_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/1e3q_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: Large Structures]] | |||
[[Category: Torpedo californica]] | [[Category: Torpedo californica]] | ||
[[Category: Felder, C E]] | [[Category: Felder, C E]] | ||