Calcium uptake protein: Difference between revisions

Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
 
Line 1: Line 1:
<StructureSection load='' size='400' side='right' caption='Human calcium uptake protein 1 complex with MPD, Cl- and Ca+2 ions (PDB code [[4nsd]])' scene='74/749964/Cv/1'>
<StructureSection load='' size='400' side='right' caption='Human mitochondrial calcium uptake protein 1 complex with MPD, Cl- and Ca+2 ions (PDB code [[4nsd]])' scene='74/749964/Cv/1'>


== Function ==
== Function ==
Line 7: Line 7:


== Disease ==
== Disease ==
Mutations in CBARA1 cause a brain and muscle disorder.
Mutations in MICU1 cause a brain and muscle disorder.


== Structural highlights ==
== Structural highlights ==
CBARA1 contains <scene name='74/749964/Cv/5'>2 Ca+2 binding sites</scene>. A <scene name='74/749964/Cv/7'>canonical EF1 site</scene> and a <scene name='74/749964/Cv/6'>canonical EF4 site</scene><ref>PMID:24514027</ref>.  
MICU1 contains <scene name='74/749964/Cv/5'>2 Ca+2 binding sites</scene>. A <scene name='74/749964/Cv/7'>canonical EF1 site</scene> and a <scene name='74/749964/Cv/6'>canonical EF4 site</scene><ref>PMID:24514027</ref>.  


== 3D Structures of calcium uptake protein ==
== 3D Structures of calcium uptake protein ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky