Intracellular receptors: Difference between revisions
No edit summary |
No edit summary |
||
Line 70: | Line 70: | ||
<scene name='57/571285/Cv/3'>PXR ligand-binding pocket is flexible and allows binding to structurally and chemically distinct ligands among them the macrolide antibiotic rifampicin</scene> which is used in testing tuberculosis. | <scene name='57/571285/Cv/3'>PXR ligand-binding pocket is flexible and allows binding to structurally and chemically distinct ligands among them the macrolide antibiotic rifampicin</scene> which is used in testing tuberculosis. | ||
*[[Retinoid X receptor]] | *[[Retinoid X receptor]] | ||
<scene name='51/516465/Cv/4'>9-cis retinoid acid binds to RXRα LBD in a hydrophobic pocket</scene>. {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}. Water molecules are shown as red spheres. <scene name='51/516465/Cv/5'>9-cis retinoid acid is in a hydrophobic pocket</scene>. The ligand-binding residues are conserved in the 3 classes of RXR. | |||
*[[Estrogen receptor]] | *[[Estrogen receptor]] | ||
*[[Ivan Koutsopatriy estrogen receptor]] | *[[Ivan Koutsopatriy estrogen receptor]] |