1b6z: Difference between revisions

No edit summary
No edit summary
Line 3: Line 3:
<StructureSection load='1b6z' size='340' side='right'caption='[[1b6z]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1b6z' size='340' side='right'caption='[[1b6z]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1b6z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[1b6z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B6Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-pyruvoyltetrahydropterin_synthase 6-pyruvoyltetrahydropterin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.12 4.2.3.12] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/6-pyruvoyltetrahydropterin_synthase 6-pyruvoyltetrahydropterin synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.12 4.2.3.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6z OCA], [http://pdbe.org/1b6z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b6z RCSB], [http://www.ebi.ac.uk/pdbsum/1b6z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6z OCA], [https://pdbe.org/1b6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b6z RCSB], [https://www.ebi.ac.uk/pdbsum/1b6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6z ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Note=Deficiency leads to phenylketonuria.  
[[https://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Note=Deficiency leads to phenylketonuria.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.  
[[https://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA