User:Jacob Holt/Sandbox 1: Difference between revisions

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	The mechanism used by the SCD1 enzyme is different than most desaturase enzymes because it does not use an oxo-bridge. This was confirmed based on the distance between the metal ions (~6.4Å) and the lack of electron density that should be present with two oxygens<ref name="Shen" />. There have been multiple proposed mechanisms, but the mechanism shown below is a shortened version of the mechanism that is the most accurate<ref name="Yu" />.		The mechanism used by the SCD1 enzyme is different than most desaturase enzymes because it does not use an oxo-bridge. This was confirmed based on the distance between the metal ions (~6.4Å) and the lack of electron density that should be present with two oxygens<ref name="Shen" />. There have been multiple proposed mechanisms, but the mechanism shown below is a shortened version of the mechanism that is the most accurate<ref name="Yu" />.



	'''Step 1''': Addition of O2 and H2O which react with the Fe2+ ions to create oxygen radicals on the iron ions (Figure 4).		'''Step 1''': Addition of O2 and H2O which react with the Fe2+ ions to create oxygen radicals on the iron ions (Figure 4).