Sandbox GGC9: Difference between revisions
No edit summary |
No edit summary |
||
| Line 24: | Line 24: | ||
Recent studies identified aspartic acid residues at positions 600 and 708 function to initiate catalysis. | Recent studies identified aspartic acid residues at positions 600 and 708 function to initiate catalysis.[7] | ||
<scene name='75/752271/Catalytic_residues/1'>Catalytic Residues</scene> | <scene name='75/752271/Catalytic_residues/1'>Catalytic Residues</scene> | ||
| Line 38: | Line 38: | ||
[4] Omenn syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program. Rarediseases.info.nih.gov. (2021). Retrieved 7 April 2021, from https://rarediseases.info.nih.gov/diseases/8198/omenn-syndrome. | [4] Omenn syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program. Rarediseases.info.nih.gov. (2021). Retrieved 7 April 2021, from https://rarediseases.info.nih.gov/diseases/8198/omenn-syndrome. | ||
[5] Gwyn, Lori M et al. “A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.” Journal of molecular biology vol. 390,5 (2009): 863-78. doi:10.1016/j.jmb.2009.05.076 | [5] Gwyn, Lori M et al. “A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.” Journal of molecular biology vol. 390,5 (2009): 863-78. doi:10.1016/j.jmb.2009.05.076 | ||
[6] Hsu, C., Yu-Yun Lee, J., & Chao, S. (2011). Omenn syndrome: a case report and review of literature. Dermatologica Sinica, 29(2). https://doi.org/doi.org/10.1016/j.dsi.2011.05.002 | [6] Hsu, C., Yu-Yun Lee, J., & Chao, S. (2011). Omenn syndrome: a case report and review of literature. Dermatologica Sinica, 29(2). https://doi.org/doi.org/10.1016/j.dsi.2011.05.002 | ||
[7] Fugmann, S., Villey, I., Ptaszek, L., & Schatz, D. (2000). Identification of Two Catalytic Residues in RAG1 that Define a Single Active Site within the RAG1/RAG2 Protein Complex. Molecular Cell, 5(1), 97-107. https://doi.org/10.1016/s1097-2765(00)80406-2 | |||