1y1u: Difference between revisions
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<StructureSection load='1y1u' size='340' side='right'caption='[[1y1u]], [[Resolution|resolution]] 3.21Å' scene=''> | <StructureSection load='1y1u' size='340' side='right'caption='[[1y1u]], [[Resolution|resolution]] 3.21Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1y1u]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1y1u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y1U FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1u OCA], [https://pdbe.org/1y1u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y1u RCSB], [https://www.ebi.ac.uk/pdbsum/1y1u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/STA5A_MOUSE STA5A_MOUSE]] Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.<ref>PMID:10508857</ref> <ref>PMID:16837552</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |