User:Tori Templin/Sandbox 1: Difference between revisions
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ACAT
References
Student Contributors
Tori Templin (talk | contribs) No edit summary |
Tori Templin (talk | contribs) No edit summary |
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== Function == | == Function == | ||
ACAT is an important enzyme that catalyzes the esterification of cholesterol to form cholesterol esters. | |||
SOAT article <ref name=”Chengcheng”>PMID:32424158</ref> | SOAT article <ref name=”Chengcheng”>PMID:32424158</ref> | ||
ACAT article <ref name=”Qian”>PMID:32433614</ref> | ACAT article <ref name=”Qian”>PMID:32433614</ref> | ||
== Disease == | == Disease == | ||
atherosclerosis, Alzheimer's Disease | |||
== Relevance == | == Relevance == | ||
Revision as of 22:33, 23 March 2021
ACATACAT
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ReferencesReferences
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
- ↑ Guan C, Niu Y, Chen SC, Kang Y, Wu JX, Nishi K, Chang CCY, Chang TY, Luo T, Chen L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 2020 May 18;11(1):2478. doi: 10.1038/s41467-020-16288-4. PMID:32424158 doi:http://dx.doi.org/10.1038/s41467-020-16288-4
- ↑ Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N. Structural basis for catalysis and substrate specificity of human ACAT1. Nature. 2020 May;581(7808):333-338. doi: 10.1038/s41586-020-2290-0. Epub 2020 May, 13. PMID:32433614 doi:http://dx.doi.org/10.1038/s41586-020-2290-0
Student ContributorsStudent Contributors
- Tori Templin
- Haylie Moehlenkamp
- Megan Fleshman