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==NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2== | ==NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2== | ||
<StructureSection load='2gmo' size='340' side='right' caption='[[2gmo]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | <StructureSection load='2gmo' size='340' side='right'caption='[[2gmo]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2gmo]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2gmo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/I75a3 I75a3]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GMO FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jdq|2jdq]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jdq|2jdq]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pb2 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pb2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=392809 I75A3])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gmo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gmo OCA], [https://pdbe.org/2gmo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gmo RCSB], [https://www.ebi.ac.uk/pdbsum/2gmo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gmo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/PB2_I75A3 PB2_I75A3]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[RNA polymerase|RNA polymerase]] | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: I75a3]] | [[Category: I75a3]] | ||
[[Category: Large Structures]] | |||
[[Category: Boudet, J]] | [[Category: Boudet, J]] | ||
[[Category: Bougault, C M]] | [[Category: Bougault, C M]] | ||