2g3q: Difference between revisions

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==Solution Structure of Ede1 UBA-ubiquitin complex==
==Solution Structure of Ede1 UBA-ubiquitin complex==
<StructureSection load='2g3q' size='340' side='right' caption='[[2g3q]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2g3q' size='340' side='right'caption='[[2g3q]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2g3q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G3Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[2g3q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3Q FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ede1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ede1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3q OCA], [http://pdbe.org/2g3q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g3q RCSB], [http://www.ebi.ac.uk/pdbsum/2g3q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3q OCA], [https://pdbe.org/2g3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3q RCSB], [https://www.ebi.ac.uk/pdbsum/2g3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EDE1_YEAST EDE1_YEAST]] Functions at the internalization step of the clathrin-mediated endocytosis (CME) as an early-acting scaffold protein. Requires clathrin adapter proteins, ENT1/2 and YAP1801/2, for normal spatiotemporal dynamics and viability. Binds to biological membranes in a ubiquitin-dependent manner.<ref>PMID:10954428</ref> <ref>PMID:12529323</ref> <ref>PMID:16239147</ref> <ref>PMID:18448668</ref> <ref>PMID:19713939</ref> <ref>PMID:19776351</ref> <ref>PMID:22190733</ref>   
[[https://www.uniprot.org/uniprot/EDE1_YEAST EDE1_YEAST]] Functions at the internalization step of the clathrin-mediated endocytosis (CME) as an early-acting scaffold protein. Requires clathrin adapter proteins, ENT1/2 and YAP1801/2, for normal spatiotemporal dynamics and viability. Binds to biological membranes in a ubiquitin-dependent manner.<ref>PMID:10954428</ref> <ref>PMID:12529323</ref> <ref>PMID:16239147</ref> <ref>PMID:18448668</ref> <ref>PMID:19713939</ref> <ref>PMID:19776351</ref> <ref>PMID:22190733</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Ubiquitin|Ubiquitin]]
*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
*[[3D structures of ubiquitin|3D structures of ubiquitin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Hicke, L]]
[[Category: Hicke, L]]
[[Category: Radhakrishnan, I]]
[[Category: Radhakrishnan, I]]

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