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==== | ==Crystal Structure of PA1607, a Putative Transcription Factor== | ||
<StructureSection load='2f2e' size='340' side='right'caption='[[2f2e]]' scene=''> | <StructureSection load='2f2e' size='340' side='right'caption='[[2f2e]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2E FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [https://pdbe.org/2f2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [https://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2e ProSAT], [https://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA1607 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [https://pdbe.org/2f2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [https://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2e ProSAT], [https://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr> | |||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2e ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2e ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607. | |||
The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537<ref>PMID:17322537</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2f2e" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Cuff, M]] | ||
[[Category: Edwards, A]] | |||
[[Category: Joachimiak, A]] | |||
[[Category: Lunin, V]] | |||
[[Category: Structural genomic]] | |||
[[Category: Sanders, D A]] | |||
[[Category: Savchenko, A]] | |||
[[Category: Sieminska, E A]] | |||
[[Category: Xu, X]] | |||
[[Category: Zheng, H]] | |||
[[Category: Apc5613]] | |||
[[Category: Helix-trun-helix]] | |||
[[Category: Mcsg]] | |||
[[Category: PSI, Protein structure initiative]] | |||
[[Category: Transcription factor]] | |||
Revision as of 12:18, 24 February 2021
Crystal Structure of PA1607, a Putative Transcription FactorCrystal Structure of PA1607, a Putative Transcription Factor
Structural highlights
Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedThe structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607. The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References |
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