2db1: Difference between revisions
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==Solution structure of the RNA binding domain in heterogeneous nuclear ribonucleoprotein F homolog== | ==Solution structure of the RNA binding domain in heterogeneous nuclear ribonucleoprotein F homolog== | ||
<StructureSection load='2db1' size='340' side='right' caption='[[2db1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2db1' size='340' side='right'caption='[[2db1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2db1]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2db1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DB1 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hnRNP F ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hnRNP F ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2db1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2db1 OCA], [https://pdbe.org/2db1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2db1 RCSB], [https://www.ebi.ac.uk/pdbsum/2db1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2db1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2db1 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/HNRPF_MOUSE HNRPF_MOUSE]] Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Nucleoprotein|Nucleoprotein]] | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Abe, C]] | [[Category: Abe, C]] |