Regulatory protein E2: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load=' | <StructureSection load='2ayg' size='340' side='right' caption='Human papillomavirus 6a regulatory protein E2 complex with DNA (PDB code=[[2ayg]])' scene=''> | ||
'''Regulatory protein E2''' (RPE2) is a human papillomavirus (HPV) protein which is required for its replication. RPE2 targets the helicase '''Regulatory protein E1''' (RPE1) to the origin of replication (ori). The HPV ori contains one RPE1 binding site and 2 RPE2 binding sites<ref>PMID:11504556</ref>. RPE2 is found also in bovine papillomavirus (BPV). | '''Regulatory protein E2''' (RPE2) is a human papillomavirus (HPV) protein which is required for its replication. RPE2 targets the helicase '''Regulatory protein E1''' (RPE1) to the origin of replication (ori). The HPV ori contains one RPE1 binding site and 2 RPE2 binding sites<ref>PMID:11504556</ref>. RPE2 is found also in bovine papillomavirus (BPV). | ||
| Line 5: | Line 5: | ||
== Disease == | == Disease == | ||
RPE2 induces apoptosis of its host cells<ref>PMID:26906543</ref>. | |||
== Relevance == | == Relevance == | ||