Vasodilator-stimulated phosphoprotein: Difference between revisions
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<StructureSection load='' size='350' side='right' caption='Human VASP (dark olive) complex with α-actin (cyan), profilin-1 (green), ATP (stick model) and Ca+2 ion (green), [[2pbd]]' scene='50/508423/Cv/ | <StructureSection load='' size='350' side='right' caption='Human VASP (dark olive) complex with α-actin (cyan), profilin-1 (green), ATP (stick model) and Ca+2 ion (green), [[2pbd]]' scene='50/508423/Cv/7' pspeed='8'> | ||
== Function == | == Function == | ||
'''Vasodilator-stimulated phosphoprotein''' (VASP) belongs to the Ena-VASP family. It binds proteins with E/DFPPPPXD/E motif and targets them to focal adhesion cell membranes. VASP is an actin- and profilin-binding protein<ref>PMID:16197368</ref>. VASP is associated with filament formation and promotes elongation. | '''Vasodilator-stimulated phosphoprotein''' (VASP) belongs to the Ena-VASP family. It binds proteins with E/DFPPPPXD/E motif and targets them to focal adhesion cell membranes. VASP is an actin- and profilin-binding protein<ref>PMID:16197368</ref>. VASP is associated with filament formation and promotes elongation. | ||
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==Structural highlights == | ==Structural highlights == | ||
VAS binds actin with a | VAS binds actin with a poly-Pro site<ref>PMID:17914456</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structure of vasodilator-stimulated phosphoprotein== | ==3D structure of vasodilator-stimulated phosphoprotein== | ||