Retroviral integrase 3D structures: Difference between revisions
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*Human immunodeficiency virus 1 integrase; Domains – N-terminal zinc-binding 728-773; catalytic core 50-212; C-terminal 219-273; C-terminal DBD 947-997; CCD 1197-1359 | *Human immunodeficiency virus 1 integrase; Domains – N-terminal zinc-binding 728-773; catalytic core 50-212; C-terminal 219-273; C-terminal DBD 947-997; CCD 1197-1359 | ||
**[[5oi5]], [[5oi3]], [[5oi2]], [[1itg]], [[6jcg]], [[6jcf]] – IN catalytic core domain <br /> | **[[6u8q]], [[6vdk]] – IN 1-288 + DNA – Cryo EM <br /> | ||
**[[3lpt]], [[3lpu]], [[3l3u]], [[1exq]], [[1b92]], [[1b9d]], [[1b9f]], [[1bi4]], [[1bhl]], [[1bl3]], [[1bis]], [[1biu]], [[1biz]], [[2itg]], [[3zcm]], [[5jl4]] - IN catalytic core domain (mutant) – HIV-1<br /> | **[[5oi5]], [[5oi3]], [[5oi2]], [[1itg]], [[6jcg]], [[6jcf]], [[6vrg]] – IN catalytic core domain <br /> | ||
**[[3lpt]], [[3lpu]], [[3l3u]], [[1exq]], [[1b92]], [[1b9d]], [[1b9f]], [[1bi4]], [[1bhl]], [[1bl3]], [[1bis]], [[1biu]], [[1biz]], [[2itg]], [[3zcm]], [[5jl4]], [[6l0c]] - IN catalytic core domain (mutant) – HIV-1<br /> | |||
**[[3l3v ]]- IN catalytic core domain (mutant) + sucrose<br /> | **[[3l3v ]]- IN catalytic core domain (mutant) + sucrose<br /> | ||
**[[1k6y]] - IN N-terminal + catalytic core domain<br /> | **[[1k6y]] - IN N-terminal + catalytic core domain<br /> | ||
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**[[1qmc]] – IN DBD - NMR<br /> | **[[1qmc]] – IN DBD - NMR<br /> | ||
**[[2b4j]], [[3av9]], [[3ava]], [[3avb]], [[3avc]], [[3avf]], [[3avg]], [[3avh]], [[3avi]], [[3avj]], [[3avk]], [[3avl]], [[3avm]], [[3avn]], [[1qs4]] - IN CCD domain (mutant) + lens epithelium-derived growth factor <br /> | **[[2b4j]], [[3av9]], [[3ava]], [[3avb]], [[3avc]], [[3avf]], [[3avg]], [[3avh]], [[3avi]], [[3avj]], [[3avk]], [[3avl]], [[3avm]], [[3avn]], [[1qs4]] - IN CCD domain (mutant) + lens epithelium-derived growth factor <br /> | ||
**[[6ex9]], [[5krt]], [[5krs]], [[5kgx]], [[5kgw]], [[4o0j]], [[1hyv]], [[1hyz]] – IN catalytic core domain + inhibitor <br /> | **[[6ex9]], [[5krt]], [[5krs]], [[5kgx]], [[5kgw]], [[4o0j]], [[1hyv]], [[1hyz]], [[6um8]], [[6vlm]] – IN catalytic core domain + inhibitor <br /> | ||
**[[3nf6]], [[3nf7]], [[3nf8]], [[3nf9]], [[3nfa]], [[4e1m]], [[4e1n]], [[4cj4]], [[4jlh]], [[4ojr]], [[5hrs]], [[5hrr]], [[5hrp]], [[5hrn]], [[5hot]], [[4tsx]], [[4ovl]], [[4ojr]], [[4o5b]], [[4o55]], [[4nyf]], [[6nuj]], [[6ncj]], [[6eb2]], [[6eb1]] - IN core domain (mutant) + inhibitor<br /> | **[[3nf6]], [[3nf7]], [[3nf8]], [[3nf9]], [[3nfa]], [[4e1m]], [[4e1n]], [[4cj4]], [[4jlh]], [[4ojr]], [[5hrs]], [[5hrr]], [[5hrp]], [[5hrn]], [[5hot]], [[4tsx]], [[4ovl]], [[4ojr]], [[4o5b]], [[4o55]], [[4nyf]], [[6nuj]], [[6ncj]], [[6eb2]], [[6eb1]], [[6lmi]], [[6lmq]], [[6ncj]], [[6nuj]] - IN core domain (mutant) + inhibitor<br /> | ||
**[[5tc2]] – IN C terminal <br /> | **[[5tc2]] – IN C terminal <br /> | ||
**[[5eu7]] – IN catalytic core domain + antibody <br /> | **[[5eu7]] – IN catalytic core domain + antibody <br /> | ||
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*Human immunodeficiency virus 2 integrase | *Human immunodeficiency virus 2 integrase | ||
**[[6qbt]] – IN catalytic core domain <br /> | |||
**[[3f9k]] - IN N-terminal + catalytic core domain + LEDGF IBD – HIV-2<br /> | **[[3f9k]] - IN N-terminal + catalytic core domain + LEDGF IBD – HIV-2<br /> | ||
**[[1e0e]] - IN N-terminal – NMR | **[[1e0e]] - IN N-terminal – NMR | ||
*Human T-cell leukemia virus | |||
**[[6qbv]], [[6qbw]] – IN catalytic core domain <br /> | |||
*Moloney murine leukemia virus integrase | *Moloney murine leukemia virus integrase | ||
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*Phage integrase | *Phage integrase | ||
**[[3bvp]] – | **[[3bvp]] – IN N-terminal – Lactococcus phage <br /> | ||
**[[1aih]] – HP1 | **[[1aih]] – HP1 IN catalytic domain – bacteriophage<br /> | ||
**[[5dor]], [[5c6k]] – IN catalytic domain – Enterobacteria phage P2 <br /> | **[[5dor]], [[5c6k]] – IN catalytic domain – Enterobacteria phage P2 <br /> | ||
**[[2wcc]], [[1kjk]] – λIN DBD+ DNA – Enterobacteria phage λ - NMR<br /> | **[[2wcc]], [[1kjk]] – λIN DBD+ DNA – Enterobacteria phage λ - NMR<br /> | ||