5yni: Difference between revisions
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==Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG== | ==Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG== | ||
<StructureSection load='5yni' size='340' side='right' caption='[[5yni]], [[Resolution|resolution]] 2.07Å' scene=''> | <StructureSection load='5yni' size='340' side='right'caption='[[5yni]], [[Resolution|resolution]] 2.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5yni]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YNI OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5yni]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YNI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5YNI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5yni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yni OCA], [http://pdbe.org/5yni PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yni RCSB], [http://www.ebi.ac.uk/pdbsum/5yni PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yni ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Chen, Y]] | [[Category: Chen, Y]] | ||
[[Category: Fan, C P]] | [[Category: Fan, C P]] | ||
Revision as of 12:23, 21 October 2020
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppGCrystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG
Structural highlights
Function[K4LC41_9BETC] Nsp7-nsp8 hexadecamer may possibly confer processivity to the polymerase, maybe by binding to dsRNA or by producing primers utilized by the latter (By similarity).[SAAS:SAAS014829_004_014545] Nsp9 is a ssRNA-binding protein (By similarity).[SAAS:SAAS014829_004_001449] |
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