5wbq: Difference between revisions
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==Structure of human Ketohexokinase complexed with hits from fragment screening== | ==Structure of human Ketohexokinase complexed with hits from fragment screening== | ||
<StructureSection load='5wbq' size='340' side='right' caption='[[5wbq]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='5wbq' size='340' side='right'caption='[[5wbq]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5wbq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WBQ OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5wbq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WBQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WBQ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A3J:2-ethyl-7-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile'>A3J</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3J:2-ethyl-7-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile'>A3J</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ketohexokinase Ketohexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.3 2.7.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ketohexokinase Ketohexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.3 2.7.1.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wbq OCA], [http://pdbe.org/5wbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wbq RCSB], [http://www.ebi.ac.uk/pdbsum/5wbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wbq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5wbq" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5wbq" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Ketohexokinase|Ketohexokinase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Ketohexokinase]] | [[Category: Ketohexokinase]] | ||
[[Category: Large Structures]] | |||
[[Category: Pandit, J]] | [[Category: Pandit, J]] | ||
[[Category: Fragment-based drug discovery]] | [[Category: Fragment-based drug discovery]] | ||
[[Category: Sbdd]] | [[Category: Sbdd]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||