3ecg: Difference between revisions

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==High Resolution HIV-2 Protease Structure in Complex with Antiviral Inhibitor GRL-98065==
==High Resolution HIV-2 Protease Structure in Complex with Antiviral Inhibitor GRL-98065==
<StructureSection load='3ecg' size='340' side='right' caption='[[3ecg]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
<StructureSection load='3ecg' size='340' side='right'caption='[[3ecg]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ecg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-2 Hiv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ECG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ECG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ecg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-2 Hiv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ECG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3ECG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=065:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE'>065</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=065:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE'>065</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ebz|3ebz]], [[3ec0|3ec0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ebz|3ebz]], [[3ec0|3ec0]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-2_retropepsin HIV-2 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.47 3.4.23.47] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-2_retropepsin HIV-2 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.47 3.4.23.47] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ecg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ecg OCA], [http://pdbe.org/3ecg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ecg RCSB], [http://www.ebi.ac.uk/pdbsum/3ecg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ecg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ecg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ecg OCA], [http://pdbe.org/3ecg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ecg RCSB], [http://www.ebi.ac.uk/pdbsum/3ecg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ecg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
*[[Immunodeficiency virus protease|Immunodeficiency virus protease]]
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
*[[Integrase|Integrase]]
*[[Integrase|Integrase]]
== References ==
== References ==
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[[Category: HIV-2 retropepsin]]
[[Category: HIV-2 retropepsin]]
[[Category: Hiv-2]]
[[Category: Hiv-2]]
[[Category: Large Structures]]
[[Category: Kovalevsky, A Y]]
[[Category: Kovalevsky, A Y]]
[[Category: Weber, I T]]
[[Category: Weber, I T]]

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