MDM2 3D structures: Difference between revisions
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*'''MDM2''' | *'''MDM2''' ); Domains – p53-binding 24-220; ring – 383-446; C4 zinc-finger 429-491 | ||
**[[2ruh]] - hMDM2 p53-binding domain | **[[2ruh]] - hMDM2 p53-binding domain - human<br /> | ||
**[[1z1m]] – hMDM2 p53-binding domain - NMR<br /> | **[[1z1m]] – hMDM2 p53-binding domain - NMR<br /> | ||
**[[2c6a]], [[2c6b]] – hMDM2 C4 Zinc-finger domain | **[[2c6a]], [[2c6b]] – hMDM2 C4 Zinc-finger domain - NMR<br /> | ||
**[[2hdp]] - hMDM2 C4 ring-finger domain | **[[2hdp]] - hMDM2 C4 ring-finger domain - NMR<br /> | ||
**[[6sqp]] - cMDM2 C4 ring-finger domain – cat<br /> | |||
**[[4ipf]], [[4j74]] – fMDM2 p53-binding domain (mutant) - frog<br /> | **[[4ipf]], [[4j74]] – fMDM2 p53-binding domain (mutant) - frog<br /> | ||
*MDM2 complex with small molecule | *MDM2 p53-binding domain complex with small molecule | ||
**[[1rv1]], [[1t4e]], [[3lbk]], [[4dij]], [[3vzv]], [[3w69]], [[3lkb]], [[4lwt]], [[4lwu]], [[4lwv]], [[4oq3]], [[5hmh]], [[5hmi]], [[5hmk]] – hMDM2 (mutant) | **[[1rv1]], [[1t4e]], [[3lbk]], [[4dij]], [[3vzv]], [[3w69]], [[3lkb]], [[4lwt]], [[4lwu]], [[4lwv]], [[4oq3]], [[5hmh]], [[5hmi]], [[5hmk]] – hMDM2 (mutant) + inhibitor<br /> | ||
**[[3jzk]], [[3lbl]], [[3tu1]], [[4ere]], [[4erf]], [[3tj2]], [[4hbm]], [[4jv7]], [[4jv9]], [[4jve]], [[4jvr]], [[4jwr]], [[4mdn]], [[4mdq]], [[4oas]], [[4oba]], [[4occ]], [[4ode]], [[4odf]], [[4ogn]], [[4ogt]], [[4ogv]], [[4qo4]], [[4hg7]], [[4wt2]], [[4qoc]], [[4wt2]], [[4zfi]], [[4zgk]], [[4zyf]], [[4zyi]], [[5j7f]], [[5j7g]], [[5lav]], [[5law]], [[5lay]], [[5laz]], [[5ln2]], [[5trf]], [[6q96]], [[6q9h]], [[6q9l]], [[6q9o]], [[6i3s]], [[6ggn]], [[5oc8]], [[5oai]] - hMDM2 | **[[3jzk]], [[3lbl]], [[3tu1]], [[4ere]], [[4erf]], [[3tj2]], [[4hbm]], [[4jv7]], [[4jv9]], [[4jve]], [[4jvr]], [[4jwr]], [[4mdn]], [[4mdq]], [[4oas]], [[4oba]], [[4occ]], [[4ode]], [[4odf]], [[4ogn]], [[4ogt]], [[4ogv]], [[4qo4]], [[4hg7]], [[4wt2]], [[4qoc]], [[4wt2]], [[4zfi]], [[4zgk]], [[4zyf]], [[4zyi]], [[5j7f]], [[5j7g]], [[5lav]], [[5law]], [[5lay]], [[5laz]], [[5ln2]], [[5trf]], [[6q96]], [[6q9h]], [[6q9l]], [[6q9o]], [[6i3s]], [[6ggn]], [[5oc8]], [[5oai]], [[6i29]] - hMDM2 + inhibitor<br /> | ||
**[[5z02]], [[5zxf]] - hMDM2 | **[[5z02]], [[5zxf]] - hMDM2 + nutlin<br /> | ||
**[[2lzg]] - hMDM2 | **[[2lzg]] - hMDM2 + inhibitor – NMR<br /> | ||
**[[3vbg]] - hMDM2 | **[[3vbg]] - hMDM2 + indolyl hydantoin<br /> | ||
**[[5c5a]] - hMDM2 (mutant) | **[[5c5a]] - hMDM2 (mutant) + inhibitor – NMR<br /> | ||
**[[1ttv]] - fMDM2 (mutant) | **[[1ttv]] - fMDM2 (mutant) + inhibitor – NMR<br /> | ||
**[[4j3e]], [[4j7d]], [[4j7e]], [[4jrg]], [[4jsc]], [[4zyc]], [[4lwt]], [[4lwu]], [[4lwv]] - fMDM2 | **[[4j3e]], [[4j7d]], [[4j7e]], [[4jrg]], [[4jsc]], [[4zyc]], [[4lwt]], [[4lwu]], [[4lwv]] - fMDM2 (mutant) + inhibitor<br /> | ||
*MDM2 complex with peptide | *MDM2 complex with peptide | ||
**[[1t4f]], [[4hfz]] - hMDM2 (mutant) p53-binding domain + p53 peptide<br /> | **[[1t4f]], [[4hfz]] - hMDM2 (mutant) p53-binding domain + p53 peptide<br /> | ||
**[[3v3b]] - hMDM2 p53-binding domain + p53 peptide<br /> | **[[3v3b]] - hMDM2 p53-binding domain + p53 peptide<br /> | ||
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**[[3jzs]] - hMDM2 p53-binding domain + pDIQ peptide<br /> | **[[3jzs]] - hMDM2 p53-binding domain + pDIQ peptide<br /> | ||
**[[3tpx]] - hMDM2 p53-binding domain + D-peptide inhibitor<br /> | **[[3tpx]] - hMDM2 p53-binding domain + D-peptide inhibitor<br /> | ||
**[[2axi]], [[2gv2]], [[3eqs]], [[3g03]], [[3iux]], [[3lnj]], [[3lnz]], [[3iwy]], [[5umm]] - hMDM2 p53-binding domain + peptide<br /> | **[[2axi]], [[2gv2]], [[3eqs]], [[3g03]], [[3iux]], [[3lnj]], [[3lnz]], [[3iwy]], [[5umm]], ]]6hfa]] - hMDM2 p53-binding domain + peptide<br /> | ||
**[[5vk0]], [[6kzu]], [[6aaw]] - hMDM2 p53-binding domain + stapled peptide<br /> | **[[5vk0]], [[6kzu]], [[6aaw]] - hMDM2 p53-binding domain + stapled peptide<br /> | ||
**[[4ud7]], [[4ue1]], [[4umn]], [[5afg]], [[5xxk]], [[6h22]] - hMDM2 p53-binding domain (mutant) + stapled peptide<br /> | **[[4ud7]], [[4ue1]], [[4umn]], [[5afg]], [[5xxk]], [[6h22]], [[6t2d]], [[6t2e]], [[6t2f]], [[6y4q]] - hMDM2 p53-binding domain (mutant) + stapled peptide<br /> | ||
**[[2m86]] - hMDM2 p53-binding domain + cyclotide - NMR<br /> | **[[2m86]] - hMDM2 p53-binding domain + cyclotide - NMR<br /> | ||
**[[2vje]], [[2vjf]] - hMDM2 ring domain + MDM4 peptide<br /> | **[[2vje]], [[2vjf]] - hMDM2 ring domain + MDM4 peptide<br /> | ||
**[[1ycq]], [[1ycr]] – fMDM2 p53-binding domain + p53 peptide <br /> | |||
*MDM2 complex with protein | *MDM2 complex with protein | ||
**[[5mnj]] - hMDM2 | **[[5mnj]] - hMDM2 C4 zinc-finger domain + MDM4 + polyubiquitin + ubiquitin-conjugating enzyme E2<br /> | ||
**[[5wts]] - hMDM2 p53-binding domain + GFP-linked peptide<br /> | **[[5wts]] - hMDM2 p53-binding domain + GFP-linked peptide<br /> | ||
**[[5swk]] - hMDM2 p53-binding domain + cysteine protease inhibitor<br /> | **[[5swk]] - hMDM2 p53-binding domain + cysteine protease inhibitor<br /> | ||
**[[6im9]] - hMDM2 p53-binding domain + copper reflux oxidase<br /> | **[[6im9]] - hMDM2 p53-binding domain + copper reflux oxidase<br /> | ||
**[[6sqo]] - hMDM2 ring domain + ubiquitin-conjugating enzyme E2 + S27A<br /> | |||
**[[6sqr]], [[6sqs]] - cMDM2 ring domain + ubiquitin-conjugating enzyme E2 + S27A<br /> | |||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||