Epoxide hydrolase: Difference between revisions

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== Function ==
== Function ==


'''Epoxide hydrolase''' (EH) converts epoxides to trans-dihydrodiols which are excreted from the body.  Thus, EH acts as a detoxification agent.  Epoxides are formed from degradation of aromatic compounds<ref>PMID:18585390</ref>.<br />  '''Bifunctional EH 2''' or '''soluble EH''' (SEH) is a bifunctional enzyme with the C-terminal domain having EH activity and the N-terminal domain having lipid phosphatase activity.<br />  '''Limonene-1,2-epoxide hydrolase''' catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol<ref>PMID:12773375</ref> .
'''Epoxide hydrolase''' (EH) converts epoxides to trans-dihydrodiols which are excreted from the body.  Thus, EH acts as a detoxification agent.  Epoxides are formed from degradation of aromatic compounds<ref>PMID:18585390</ref>.<br />  '''Bifunctional EH 2''' or '''soluble EH''' (SEH) is a bifunctional enzyme with the C-terminal domain having EH activity and the N-terminal domain having lipid phosphatase activity.<br />  '''Limonene-1,2-epoxide hydrolase''' catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol<ref>PMID:12773375</ref> .  For details see [[limonene-1,2-epoxide hydrolase]].


== Disease ==
== Disease ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman