Interleukin-1 receptor-associated kinase: Difference between revisions
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IRAK4 deficiency is a disorder which causes recurrent bacterial infections. | IRAK4 deficiency is a disorder which causes recurrent bacterial infections. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of interleukin receptor-associated kinase== | ==3D structures of interleukin-1 receptor-associated kinase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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**[[5uke]] – hIRAK3 DEATH domain (mutant) - NMR<br /> | **[[5uke]] – hIRAK3 DEATH domain (mutant) - NMR<br /> | ||
**[[6ziw]] – hIRAK3 residues 141-455 + ATPγS <br /> | |||
*IRAK4 kinase domain residues 30-336; DEATH domain residues 4-106 | *IRAK4 kinase domain residues 30-336; DEATH domain residues 4-106 | ||
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**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br /> | **[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br /> | ||
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br /> | **[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br /> | ||
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]], [[6n8g]], [[6o8u]], [[6o94]], [[6o95]], [[6o9d]] - hIRAK4 kinase domain + inhibitor<br /> | **[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]], [[6n8g]], [[6o8u]], [[6o94]], [[6o95]], [[6o9d]], [[6uya]], [[6vql]] - hIRAK4 kinase domain + inhibitor<br /> | ||
**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]], [[6ega]], [[6eg9]], [[6egd]], [[6ege]], [[6egf]] - hIRAK4 residues 154-460 + inhibitor<br /> | **[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]], [[6ega]], [[6eg9]], [[6egd]], [[6ege]], [[6egf]], [[6mom]], [[6rfi]], [[6rfj] - hIRAK4 residues 154-460 + inhibitor<br /> | ||
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br /> | **[[2oid]] - hIRAK4 kinase domain + AMPPNP<br /> | ||
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br /> | **[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br /> | ||