5mim: Difference between revisions
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==Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n== | ==Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n== | ||
<StructureSection load='5mim' size='340' side='right' caption='[[5mim]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5mim' size='340' side='right'caption='[[5mim]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5mim]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MIM OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5mim]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MIM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MIM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1N:1-[(1~{R},2~{R},4~{S},5~{S})-2,4-BIS(4-CARBAMIMIDAMIDOPHENOXY)-5-[(4-CARBAMIMIDAMIDOPHENYL)AMINO]CYCLOHEXYL]GUANIDINE'>1N</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1N:1-[(1~{R},2~{R},4~{S},5~{S})-2,4-BIS(4-CARBAMIMIDAMIDOPHENOXY)-5-[(4-CARBAMIMIDAMIDOPHENYL)AMINO]CYCLOHEXYL]GUANIDINE'>1N</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Furin Furin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.75 3.4.21.75] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Furin Furin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.75 3.4.21.75] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mim OCA], [http://pdbe.org/5mim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mim RCSB], [http://www.ebi.ac.uk/pdbsum/5mim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mim ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5mim" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5mim" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Furin|Furin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Furin]] | [[Category: Furin]] | ||
[[Category: Large Structures]] | |||
[[Category: Dahms, S O]] | [[Category: Dahms, S O]] | ||
[[Category: Guan-Sheng, J]] | [[Category: Guan-Sheng, J]] | ||