6v7h: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of CTX-M-14 bound to Vaborbactam at 1.0 A== | ==Structure of CTX-M-14 bound to Vaborbactam at 1.0 A== | ||
<StructureSection load='6v7h' size='340' side='right'caption='[[6v7h]]' scene=''> | <StructureSection load='6v7h' size='340' side='right'caption='[[6v7h]], [[Resolution|resolution]] 1.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V7H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V7H FirstGlance]. <br> | <table><tr><td colspan='2'>[[6v7h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V7H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V7H FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v7h OCA], [http://pdbe.org/6v7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v7h RCSB], [http://www.ebi.ac.uk/pdbsum/6v7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v7h ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4D6:{(3R,6S)-2-HYDROXY-3-[(THIOPHEN-2-YLACETYL)AMINO]-1,2-OXABORINAN-6-YL}ACETIC+ACID'>4D6</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=WXM:2-[(3~{R},6~{S})-2,2-bis(oxidanyl)-3-(2-thiophen-2-ylethanoylamino)-1-oxa-2-boranuidacyclohex-6-yl]ethanoic+acid'>WXM</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaCTX-M-14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v7h OCA], [http://pdbe.org/6v7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v7h RCSB], [http://www.ebi.ac.uk/pdbsum/6v7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v7h ProSAT]</span></td></tr> | |||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | |||
[[Category: Beta-lactamase]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen Y]] | [[Category: Chen, Y]] | ||
[[Category: Pemberton | [[Category: Pemberton, O A]] | ||
[[Category: Boronate]] | |||
[[Category: Esbl]] | |||
[[Category: Hydrolase]] | |||
[[Category: Inhibitor]] | |||