Proteopedia:Featured SEL/6: Difference between revisions

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 <tr><td><div class='scrolling '>'''Coronavirus Spike Protein Membrane Fusion'''<br>
 ''by Eric Martz''<br>
-SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. Similar conformational transformations have been observed for the spike protein of SARS-CoV and mouse hepatitis virus, among others. These rearrangements also have much in common with the membrane fusion mechansism of influenza hemagglutinin.
+SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. It "spears" the host membrane with a <font color="#0060ff">'''fusion peptide'''</font> and drags the virus envelope membrane <font color="red">'''transmembrane domain'''</font> to contact the host membrane, initiating fusion. This moves the virus RNA genome into the host cell, initiating fusion.
 >>> [[SARS-CoV-2_spike_protein_fusion_transformation|Visit this page]] >>>
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