SARS-CoV-2 spike protein fusion transformation: Difference between revisions

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			SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that is believed to play a central role in fusing the coronavirus membrane with the host cell membrane<ref name="cai-zheng">PMID: 32694201</ref>. Similar conformational transformations have been observed for the spike protein of SARS-CoV and mouse hepatitis virus. These rearrangements also have much in common with the membrane fusion mechansism of influenza hemagglutinin.