2ypn: Difference between revisions

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==Hydroxymethylbilane synthase==
==Hydroxymethylbilane synthase==
<StructureSection load='2ypn' size='340' side='right' caption='[[2ypn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2ypn' size='340' side='right'caption='[[2ypn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ypn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YPN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ypn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YPN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylbilane_synthase Hydroxymethylbilane synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.61 2.5.1.61] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylbilane_synthase Hydroxymethylbilane synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.61 2.5.1.61] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ypn OCA], [http://pdbe.org/2ypn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ypn RCSB], [http://www.ebi.ac.uk/pdbsum/2ypn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ypn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ypn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ypn OCA], [http://pdbe.org/2ypn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ypn RCSB], [http://www.ebi.ac.uk/pdbsum/2ypn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ypn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
[[Category: Hydroxymethylbilane synthase]]
[[Category: Hydroxymethylbilane synthase]]
[[Category: Large Structures]]
[[Category: Campbell, J W]]
[[Category: Campbell, J W]]
[[Category: Habash, J]]
[[Category: Habash, J]]

Revision as of 16:01, 22 July 2020

Hydroxymethylbilane synthaseHydroxymethylbilane synthase

Structural highlights

2ypn is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Hydroxymethylbilane synthase, with EC number 2.5.1.61
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ypn, resolution 2.30Å

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