2y5l: Difference between revisions
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==orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase== | ==orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase== | ||
<StructureSection load='2y5l' size='340' side='right' caption='[[2y5l]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2y5l' size='340' side='right'caption='[[2y5l]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y5l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y5L OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[2y5l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y5L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Y5L FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RO8:N-{[(2Z)-5-BROMO-1,3-THIAZOL-2(3H)-YLIDENE]CARBAMOYL}-3-CHLOROBENZENESULFONAMIDE'>RO8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RO8:N-{[(2Z)-5-BROMO-1,3-THIAZOL-2(3H)-YLIDENE]CARBAMOYL}-3-CHLOROBENZENESULFONAMIDE'>RO8</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jjk|2jjk]], [[2wbd|2wbd]], [[2fhy|2fhy]], [[2fix|2fix]], [[1fta|1fta]], [[2vt5|2vt5]], [[2fie|2fie]], [[2wbb|2wbb]], [[2y5k|2y5k]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jjk|2jjk]], [[2wbd|2wbd]], [[2fhy|2fhy]], [[2fix|2fix]], [[1fta|1fta]], [[2vt5|2vt5]], [[2fie|2fie]], [[2wbb|2wbb]], [[2y5k|2y5k]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2y5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y5l OCA], [http://pdbe.org/2y5l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y5l RCSB], [http://www.ebi.ac.uk/pdbsum/2y5l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y5l ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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==See Also== | ==See Also== | ||
*[[Fructose-1%2C6-bisphosphatase|Fructose-1%2C6-bisphosphatase]] | *[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Fructose-bisphosphatase]] | [[Category: Fructose-bisphosphatase]] | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Alvarez-sanchez, r]] | [[Category: Alvarez-sanchez, r]] | ||
[[Category: Benardeau, a]] | [[Category: Benardeau, a]] | ||