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==High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule== | ==High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule== | ||
<StructureSection load='6wvm' size='340' side='right'caption='[[6wvm]]' scene=''> | <StructureSection load='6wvm' size='340' side='right'caption='[[6wvm]], [[Resolution|resolution]] 3.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WVM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WVM FirstGlance]. <br> | <table><tr><td colspan='2'>[[6wvm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WVM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WVM FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wvm OCA], [http://pdbe.org/6wvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wvm RCSB], [http://www.ebi.ac.uk/pdbsum/6wvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wvm ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wvm OCA], [http://pdbe.org/6wvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wvm RCSB], [http://www.ebi.ac.uk/pdbsum/6wvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wvm ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/E1BJB1_BOVIN E1BJB1_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00031082] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bos taurus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cha M]] | [[Category: Cha, M]] | ||
[[Category: Debs | [[Category: Debs, G E]] | ||
[[Category: Huehn | [[Category: Huehn, A R]] | ||
[[Category: Sindelar | [[Category: Sindelar, C V]] | ||
[[Category: Microtubule]] | |||
[[Category: Structural protein]] | |||
Revision as of 17:42, 8 July 2020
High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubuleHigh curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule
Structural highlights
Function[TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [E1BJB1_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00031082] |
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