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==DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link==
==DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link==
<StructureSection load='2wtf' size='340' side='right' caption='[[2wtf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2wtf' size='340' side='right'caption='[[2wtf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wtf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WTF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wtf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WTF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WTF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jih|1jih]], [[2xgq|2xgq]], [[2xgp|2xgp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jih|1jih]], [[2xgq|2xgq]], [[2xgp|2xgp]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wtf OCA], [http://pdbe.org/2wtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wtf RCSB], [http://www.ebi.ac.uk/pdbsum/2wtf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wtf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wtf OCA], [http://pdbe.org/2wtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wtf RCSB], [http://www.ebi.ac.uk/pdbsum/2wtf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wtf ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wtf ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wtf ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Atcc 18824]]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Carell, T]]
[[Category: Carell, T]]
[[Category: Livneh, Z]]
[[Category: Livneh, Z]]

Revision as of 12:09, 1 July 2020

DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-linkDNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link

Structural highlights

2wtf is a 6 chain structure with sequence from Atcc 18824. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:DNA-directed DNA polymerase, with EC number 2.7.7.7
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2wtf, resolution 2.50Å

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