5k14: Difference between revisions
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==HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog== | ==HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog== | ||
<StructureSection load='5k14' size='340' side='right' caption='[[5k14]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='5k14' size='340' side='right'caption='[[5k14]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5k14]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K14 OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5k14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K14 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K14 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IB1:4-{[4-(2,6-DIFLUORO-4-METHOXYBENZENE-1-CARBONYL)PYRIMIDIN-2-YL]AMINO}BENZONITRILE'>IB1</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IB1:4-{[4-(2,6-DIFLUORO-4-METHOXYBENZENE-1-CARBONYL)PYRIMIDIN-2-YL]AMINO}BENZONITRILE'>IB1</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k14 OCA], [http://pdbe.org/5k14 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k14 RCSB], [http://www.ebi.ac.uk/pdbsum/5k14 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k14 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5k14" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5k14" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Reverse transcriptase 3D structures|Reverse transcriptase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1]] | |||
[[Category: Large Structures]] | |||
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] | ||
[[Category: Lansdon, E B]] | [[Category: Lansdon, E B]] | ||
[[Category: Inhibitor complex]] | [[Category: Inhibitor complex]] | ||
[[Category: Nnrti]] | [[Category: Nnrti]] | ||
[[Category: Reverse transcriptase]] | [[Category: Reverse transcriptase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||