Claire Lupton
Joined 4 March 2020
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Although there is still research being conducted on it, lengsin appears to have numerous, important roles in the mature human body. In fact, this protein has also been reported as a known tumor antigen, and it most specifically has been associated with lung cancers. | Although there is still research being conducted on it, lengsin appears to have numerous, important roles in the mature human body. In fact, this protein has also been reported as a known tumor antigen, and it most specifically has been associated with lung cancers. | ||
Studies from 2011 revealed that high levels of lengsin are present in the entire spectrum of lung cancer classifications. This is unusual because lengsin is | Studies from 2011 revealed that high levels of lengsin are present in the entire spectrum of lung cancer classifications. This is unusual because lengsin is most prominently found in the lens. In fact, in lung cancer patients, it has been observed that lengsin levels are elevated. This information is an essential clue to how to treat lung cancers. Using protein derivatives, specified antigens care can be given to carcinoma patients. For example, lengsin is a highly specific solution to lung cancers due to the body’s natural response. In treatment, lengsin can be spliced to help suppress tumors, and perform its antigenic function. Since these cancer cells naturally produce lengsin, the protein can be extracted from the surface of the lymphocyte cells. This also allows for easy binding of the cancer treatment via antigens. In this study, several variations of the protein were explored, and there were some that had higher success rates than others. It is, nonetheless, crucial to note that these studies were performed on mice, so the success rates are species specific. There is not much research supporting evidence that lengsin would be efficient at treating other types of cancers.<ref name=ref4>PMID: Nakatsugawa, M., Horie, K., Yoshikawa, T., Shimomura, M., Kikuchi, Y., Sakemura, N., … Nakatsura, T. (2011). Identification of an HLA-A*0201-restricted Cytotoxic T Lymphocyte Epitope from the Lung Carcinoma Antigdn, Lengsin. Retrieved from https://maryville.illiad.oclc.org/illiad/pdf/</ref> | ||