5epn: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of HCV NS3/4A protease in complex with 5172-mcP1P3 (MK-5172 P1-P3 macrocyclic analogue)== | ==Crystal structure of HCV NS3/4A protease in complex with 5172-mcP1P3 (MK-5172 P1-P3 macrocyclic analogue)== | ||
<StructureSection load='5epn' size='340' side='right' caption='[[5epn]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='5epn' size='340' side='right'caption='[[5epn]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5epn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPN OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5epn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EPN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5R2:2-METHYL-2-PROPANYL+{(2R,6S,12Z,13AS,14AR,16AS)-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-[(3-ETHYL-7-METHOXY-2-QUINOXALINYL)OXY]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOP+ROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL}CARBAMATE'>5R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R2:2-METHYL-2-PROPANYL+{(2R,6S,12Z,13AS,14AR,16AS)-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-[(3-ETHYL-7-METHOXY-2-QUINOXALINYL)OXY]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOP+ROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL}CARBAMATE'>5R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5epy|5epy]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5epy|5epy]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5epn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5epn OCA], [http://pdbe.org/5epn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5epn RCSB], [http://www.ebi.ac.uk/pdbsum/5epn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5epn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 21: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Ali, A]] | [[Category: Ali, A]] | ||
[[Category: Aydin, C]] | [[Category: Aydin, C]] | ||