Glucagon-like peptide 1 receptor: Difference between revisions
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<StructureSection load='3iol' size='350' side='right' scene='' caption=' | <StructureSection load='3iol' size='350' side='right' scene='' caption='Human GLP-1R extracellular domain (gray) complex with GLP-1 peptide (green) and a pyranose derivative (PDB code [[3iol]])'> | ||
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
The 3D structure of the complex of GLP-1R and GLP-1 shows the GLP-1 peptide as a kinked helix. The ampiphilic GLP-1 helix shows hydrophilic and hydrophobic interactions with GLP-1R on opposite faces<ref>PMID:19861722</ref>. | |||
</StructureSection> | </StructureSection> | ||