Glucagon-like peptide 1 receptor: Difference between revisions

Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 1: Line 1:
<StructureSection load='3iol' size='350' side='right' scene='' caption='CotA laccase complex with glycerol, O2 and Cu+2 (orange) (PDB code [[3iol]])'>
<StructureSection load='3iol' size='350' side='right' scene='' caption='Human GLP-1R extracellular domain (gray) complex with GLP-1 peptide (green) and a pyranose derivative (PDB code [[3iol]])'>
== Function ==
== Function ==


Line 10: Line 10:
== Structural highlights ==
== Structural highlights ==


 
The 3D structure of the complex of GLP-1R and GLP-1 shows the GLP-1 peptide as a kinked helix.  The ampiphilic GLP-1 helix shows hydrophilic and hydrophobic interactions with GLP-1R on opposite faces<ref>PMID:19861722</ref>.
</StructureSection>
</StructureSection>


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Karsten Theis