5djb: Difference between revisions
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==Structure of the Haliangium ochraceum BMC-H shell protein== | ==Structure of the Haliangium ochraceum BMC-H shell protein== | ||
<StructureSection load='5djb' size='340' side='right' caption='[[5djb]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='5djb' size='340' side='right'caption='[[5djb]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5djb]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DJB OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5djb]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Halo1 Halo1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DJB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DJB FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dii|5dii]], [[5dih|5dih]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dii|5dii]], [[5dih|5dih]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hoch_5815 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502025 HALO1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5djb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5djb OCA], [http://pdbe.org/5djb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5djb RCSB], [http://www.ebi.ac.uk/pdbsum/5djb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5djb ProSAT]</span></td></tr> | |||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Halo1]] | |||
[[Category: Large Structures]] | |||
[[Category: Kerfeld, C A]] | [[Category: Kerfeld, C A]] | ||
[[Category: Sutter, M]] | [[Category: Sutter, M]] | ||
[[Category: Bacterial microcompartment]] | [[Category: Bacterial microcompartment]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 11:06, 8 April 2020
Structure of the Haliangium ochraceum BMC-H shell proteinStructure of the Haliangium ochraceum BMC-H shell protein
Structural highlights
Publication Abstract from PubMedBacterial microcompartments (BMCs) are proteinaceous organelles widespread among bacterial phyla. They compartmentalize enzymes within a selectively permeable shell and play important roles in CO2 fixation, pathogenesis, and microbial ecology. Here, we combine X-ray crystallography and high-speed atomic force microscopy to characterize, at molecular resolution, the structure and dynamics of BMC shell facet assembly. Our results show that preformed hexamers assemble into uniformly oriented shell layers, a single hexamer thick. We also observe the dynamic process of shell facet assembly. Shell hexamers can dissociate from and incorporate into assembled sheets, indicating a flexible intermolecular interaction. Furthermore, we demonstrate that the self-assembly and dynamics of shell proteins are governed by specific contacts at the interfaces of shell proteins. Our study provides novel insights into the formation, interactions, and dynamics of BMC shell facets, which are essential for the design and engineering of self-assembled biological nanoreactors and scaffolds based on BMC architectures. Visualization of Bacterial Microcompartment Facet Assembly Using High-Speed Atomic Force Microscopy.,Sutter M, Faulkner M, Aussignargues C, Paasch BC, Barrett S, Kerfeld CA, Liu LN Nano Lett. 2015 Dec 7. PMID:26617073[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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