Alpha-synuclein: Difference between revisions

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== Function ==
== Function ==


'''Alpha-Synuclein''' (Syn) is a human neuronal protein which has several roles in synaptic activity. Syn enhances vesicle priming, fusion and dilation of exocytotic pores<ref>PMID:28288128/ref>.  Syn acts as a molecular chaperone in assisting the folding of SNAREs - the synaptic fusion components<ref>PMID:20798282</ref>.  Syn associates with the dopamine transporter and modulates its activity<ref>PMID:26442590</ref>.
'''Alpha-Synuclein''' (Syn) is a human neuronal protein which has several roles in synaptic activity. Syn enhances vesicle priming, fusion and dilation of exocytotic pores<ref>PMID:28288128</ref>.  Syn acts as a molecular chaperone in assisting the folding of SNAREs - the synaptic fusion components<ref>PMID:20798282</ref>.  Syn associates with the dopamine transporter and modulates its activity<ref>PMID:26442590</ref>.


== Disease ==
== Disease ==

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Michal Harel, Joel L. Sussman, Alexander Berchansky