5d26: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:


==First bromodomain of BRD4 bound to inhibitor XD28==
==First bromodomain of BRD4 bound to inhibitor XD28==
<StructureSection load='5d26' size='340' side='right' caption='[[5d26]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='5d26' size='340' side='right'caption='[[5d26]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5d26]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D26 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5d26]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D26 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=L28:N~2~-[5-(DIETHYLSULFAMOYL)-2-HYDROXYPHENYL]-3-ETHYL-5-METHYL-1H-PYRROLE-2,4-DICARBOXAMIDE'>L28</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU3:(R,R)-2,3-BUTANEDIOL'>BU3</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=L28:N~2~-[5-(DIETHYLSULFAMOYL)-2-HYDROXYPHENYL]-3-ETHYL-5-METHYL-1H-PYRROLE-2,4-DICARBOXAMIDE'>L28</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d26 OCA], [http://pdbe.org/5d26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d26 RCSB], [http://www.ebi.ac.uk/pdbsum/5d26 PDBsum]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d26 OCA], [http://pdbe.org/5d26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d26 RCSB], [http://www.ebi.ac.uk/pdbsum/5d26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d26 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
Line 22: Line 23:


==See Also==
==See Also==
*[[Bromodomain-containing protein|Bromodomain-containing protein]]
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Huegle, M]]
[[Category: Huegle, M]]
[[Category: Wohlwend, D]]
[[Category: Wohlwend, D]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA