Uridine phosphorylase: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
The <scene name='59/596312/Cv/3'>active site of UPP contains the uracil product</scene><ref>PMID:22868762</ref>. Water molecule is shown as red sphere.  
The <scene name='59/596312/Cv/3'>active site of UPP contains the uracil product</scene><ref>PMID:22868762</ref>. Water molecule is shown as red sphere.  
== 3D Structures of uridine phosphorylase =
== 3D Structures of uridine phosphorylase ==
[[Uridine phosphorylase 3D structures]]
[[Uridine phosphorylase 3D structures]]
</StructureSection>
</StructureSection>
== 3D Structures of uridine phosphorylase ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Uridine phosphorylase
**[[1k3f]], [[1lx7]], [[1rxy]], [[1t0u]] – EcUPP – ''Escherichia coli'' <br />
**[[1ryz]], [[2iq5]], [[2oxf]], [[2qdk]], [[3dps]] – StUPP – ''Salmonella typhimurium'' <br />
**[[3o6v]], [[4k6o]], [[6eyp]] – VcUPP – ''Vibrio cholerae'' <br />
**[[4i2v]], [[4ny1]], [[4of4]] – UPP – ''Yersinia pseudotuberculosis''<br />
**[[4txh]] – SmUPP – ''Schistosoma mansoni'' <br />
**[[6k5g]], [[6k5h]], [[6k5k]], [[6k8p]], [[6kd3]] – UPP – ''Phytophthora capsici'' <br />
*Uridine phosphorylase binary complex
**[[3ku4]] – bUPP + sulfate - bovine <br />
**[[1sj9]], [[2hsw]], [[2i8a]], [[3ddo]] – StUPP + phosphate  <br />
**[[1y1t]] – StUPP + sulfate  <br />
**[[2oec]], [[3c74]] – StUPP + inhibitor<br />
**[[4g8j]] – StUPP + 2’-deoxythymidine <br />
**[[4e1v]], [[4ogk]], [[4ogl]] – SeUPP + nucleotide – ''Salmonella enterica''<br />
**[[4lnh]] – VfUPP + sulfate – ''Vibrio fischeri'' <br />
**[[4h1t]], [[4ip0]] – VcUPP + phosphate  <br />
**[[5epu]] – VcUPP + cytosine <br />
**[[5our]] – VcUPP + anhydrouridine <br />
**[[4lzw]], [[4oeh]], [[5c80]], [[5epu]], [[5efo]], [[5m2t]]  – VcUPP + nucleotide <br />
**[[4u2k]] – VcUPP + anticancer compound <br />
**[[4txj]], [[4txl]], [[4txn]], [[4txm]] – SmUPP + nucleotide <br />
**[[4jp5]] – UPP + sulfate – ''Yersinia pestis''<br />
**[[4r2x]] – SoUPP + sulfate – ''Shewanella oneidensis''<br />
**[[4yjk]] – SoUPP (mutant) + uracil <br />
*Uridine phosphorylase ternary complex
**[[3kuk]] – bUPP + sulfate + 2’-deoxyuridine <br />
**[[3kvr]] – bUPP + sulfate + 5-fluorouracil <br />
**[[3kvy]] – bUPP + sulfate + uracil <br />
**[[1y1r]], [[1zl2]], [[2pga]], [[3fwp]] – StUPP + phosphate  + inhibitor<br />
**[[2rj3]] – StUPP + phosphate + uracil <br />
**[[1y1s]] – StUPP + sulfate + uracil <br />
**[[1y1q]] – StUPP + sulfate + UMP  <br />
**[[2hn9]], [[2hrd]] – StUPP + phosphate + thymine <br />
**[[2hwu]] – StUPP + phosphate + uridine <br />
**[[1rxs]] – EcUPP + phosphate + 2’-deoxyuridine <br /
**[[1rxu]] – EcUPP + phosphate + 2’-deoxythymidine <br />
**[[1tgy]] – EcUPP + ribose-1-phosphate + uracil <br />
**[[1u1c]], [[1u1d]], [[1u1e]], [[1u1f]], [[1u1g]] – EcUPP + phosphate + 5-substituted acyclouridine <br />
**[[1tgv]] – EcUPP + sulfate + 5-fluorouridine <br />
**[[3kvv]] – EcUPP + sulfate + 5-fluorouracil <br />
**[[1rxc]] – EcUPP + ribose-1-phosphate + phosphate + 5-fluorouracil + 5-fluorouridine <br />
**[[3pns]], [[5miw]] – VcUPP + sulfate + uracil <br />
**[[5lhv]] – VcUPP + sulfate + uridine <br />
**[[5efo]], [[5lok]] – VcUPP + cytosine + cytidine <br />
**[[4mch]] – VfUPP + sulfate + hydroxyl naphthoic acid <br />
**[[4mci]] – VfUPP + sulfate + DMSO <br />
**[[4r2w]] – SoUPP + sulfate + uridine <br />
**[[4yjk]] – SoUPP (mutant) + sulfate + uracil <br />
**[[3qpb]] – UPP + ribose-1-phosphate + uracil – ''Streptococcus pyogenes''<br />
*Human uridine phosphorylase
**[[3eue]] – hUPP 1 + sulfate - human  <br />
**[[3euf]] – hUPP 1 + benzylacyclouridine <br />
**[[3nbq]] – hUPP 1 + 5-fluorouracil <br />
**[[2xrf]] – hUPP 2 + uracil<br />
**[[3p0f]] – hUPP 2 + benzylacyclouridine <br />
**[[3p0e]] – hUPP 2 + phosphate + benzylacyclouridine <br />
}}


== References ==
== References ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman