Proteopedia

Tubulin: Difference between revisions

← Older editNewer edit →
Michal Harel (talk | contribs)
31,761 edits
No edit summary
Michal Harel (talk | contribs)
31,761 edits
No edit summary
Line 2: Line 2:
== Function ==
== Function ==


[[Tubulin]] (TUB) is a constituent of microtubules in eukaryotes.  Microtubules are assembled from dimers of '''α-tubulin''' (TUBA) and '''β-tubulin''' (TUBB) bound to GTP. '''γ-tubulin''' (TUBG) is part of the nucleation of microtubules<ref>PMID:11297925</ref>. Human TUB contains several numbered subtypes.  '''FtsZ'''  (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB<ref>PMID:26463348</ref>. See [[Cell division protein]] and [[Beta tubulin]].
[[Tubulin]] (TUB) is a constituent of microtubules in eukaryotes.  Microtubules are assembled from dimers of '''α-tubulin''' (TUBA) and '''β-tubulin''' (TUBB) bound to GTP. '''γ-tubulin''' (TUBG) is part of the nucleation of microtubules<ref>PMID:11297925</ref>. Human TUB contains several numbered subtypes.  Tubulin filaments are stabilized by taxol and zampanolide.  ''FtsZ'''  (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB<ref>PMID:26463348</ref>. See [[Cell division protein]] and [[Beta tubulin]].


== Relevance ==
== Relevance ==
Line 15: Line 15:
== Structural highlights ==
== Structural highlights ==
*<scene name='43/430888/Cv/6'>γ-tubulin interactions with GTP and Mg+2 ion</scene> ([[1z5w]]).
*<scene name='43/430888/Cv/6'>γ-tubulin interactions with GTP and Mg+2 ion</scene> ([[1z5w]]).
== 3D Structures of Tubulin ==
[[Tubulin 3D Structures]]
</StructureSection>
</StructureSection>
== 3D Structures of Tubulin ==
== 3D Structures of Tubulin ==
Line 28: Line 31:
*α-tubulin + β-tubulin
*α-tubulin + β-tubulin


**[[5n5n]] – hTUBA-1A+hTUB-3 + GTP + G2P – Cryo EM<br />
**[[6e7b]] – hTUBA-1B+hTUB-3 + GTP + G2P – Cryo EM<br />
**[[5ij0]] – hTUBA-1B+hTUB-3 + GTP + GDP – Cryo EM<br />
**[[5ij9]] – hTUBA-1B+hTUB-3 (mutant) + GTP + GDP – Cryo EM<br />
**[5n5n]] – hTUBA-1B+hTUB-5 + GTP + G2P – Cryo EM<br />
**[6e7c]] – hTUBA-1B+hTUB-2B + GTP + G2P – Cryo EM<br />
**[[6i2i]] – hTUBA-1B +hTUB-5 + GTP + G2P + stabilizer – Cryo EM<br />
**[[1jff]] - bTUBA+bTUBB - bovine<br />
**[[1jff]] - bTUBA+bTUBB - bovine<br />
**[[3j6f]] - pTUBA+pTUBB – pig - Cryo EM <br />
**[[3j6f]] - pTUBA+pTUBB – pig - Cryo EM <br />
Line 33: Line 43:
**[[6dpu]] - pTUBA+pTUBB +GMPCPP + GTP – Cryo EM <br />
**[[6dpu]] - pTUBA+pTUBB +GMPCPP + GTP – Cryo EM <br />
**[[3j7i]] - pTUBA+pTUBB + GTP – Cryo EM<br />
**[[3j7i]] - pTUBA+pTUBB + GTP – Cryo EM<br />
**[[6o2r]], [[6o2q]], [[5xxw]], [[5xxv]], [[5xxt]] - pTUBA+pTUBB +GTP + GDP – Cryo EM<br />
**[[5xxx]] - pTUBA+pTUBB +GTP + G2P – Cryo EM<br />
**[[6evx]], [[6evy]], [[6evz]], [[6ew0]], [[6dpv]], [[6dpw]] - pTUBA+pTUBB + GTP + GDP - Cryo EM<br />
**[[6evx]], [[6evy]], [[6evz]], [[6ew0]], [[6dpv]], [[6dpw]] - pTUBA+pTUBB + GTP + GDP - Cryo EM<br />
**[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
**[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
**[[5w3h]] - yTUBA+ yTUBB +GTP + GDP – yeast - Cryo EM<br />
**[[2btq]] – PdTUBA+PdTUBB<br />
**[[2btq]] – PdTUBA+PdTUBB<br />
**[[5w3f]] - yTUBA+yTUBB + GDP + GTP - yeast<br />
**[[5w3f]] - yTUBA+yTUBB + GDP + GTP - yeast<br />
**[[5w3j]] - yTUBA+yTUBB (mutant) + GDP + GTP + taxol<br />
**[[5w3j]] - yTUBA+yTUBB (mutant) + GDP + GTP + stabilizer<br />
**[[5ubq]], [[5ucy]] - TUBA+ TUBB  – ''Tetrahymena thermophila'' - Cryo EM <br />
**[[5ubq]], [[5ucy]] - TUBA+ TUBB  – ''Tetrahymena thermophila'' - Cryo EM <br />
**[[6e88]] - TUBA+ TUBB +GTP + GDP – ''Caenorhabditis elegans'' - Cryo EM<br />


*α-tubulin + β-tubulin complexes with stathmin-4
*α-tubulin + β-tubulin complexes with stathmin-4
Line 51: Line 65:
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
**[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
**[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
**[[6h9b]] - sTUBA+sTUBB+stathmin-4 + GDP + GTP + quinoline derivative<br />


*α-tubulin + β-tubulin complexes with stathmin-4 and tubulin-tyrosine ligase (TTL)
*α-tubulin + β-tubulin complexes with stathmin-4 and tubulin-tyrosine ligase (TTL)
Line 57: Line 72:
**[[4o2a]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ADP + drug<br />
**[[4o2a]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ADP + drug<br />
**[[4ihj]] - bTUBA+bTUBB+stathmin-4 + TTL + ADP<br />
**[[4ihj]] - bTUBA+bTUBB+stathmin-4 + TTL + ADP<br />
**[[6i5c]], [[4i55]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative<br />
**[[6i5c]], [[4i55]], [[6s9e]], [[6gze]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative<br />
**[[5jh7]], [[5xaf]], [[5xag]], [[5xlz]] - bTUBA+bTUBB+stathmin-4 + TTL + GDP + GTP + ATP derivative + drug<br />
**[[6qqn]], [[6knz]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative<br />
**[[6hx8]], [[6gj4]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + quinoline derivative<br />
**[[6k9v]], [[6jcj]], [[6fkl]], [[6fkj]], [[6f7c]], [[5z4p]], [[5yz3]], [[5nfz]], [[5lyj]] – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
**[[5ng1]] – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor + stabilizer<br />
**[[6fjf]] - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + fcmaytansine<br />
**[[6fii]], [[6fjm]], [[6gf3]], [[6qtn]], [[5jh7]], [[5bmv]], [[5la6]], [[5osk]], [[5jvd]], [[5gon]] – bTUBA + bTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent<br />
**[[5iyz]], [[5j2t]], [[5j2u]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]] – bTUBAB1 +bTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + auristatin anti-mitotics<br />
**[[5iyz]], [[5j2t]], [[5j2u]], [[4tv9]], [[4yj2]], [[4yj3]], [[2xrp]] – bTUBAB1 +bTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + auristatin anti-mitotics<br />
**[[4o2b]] - bTUBA+bTUBB+stathmin-4 + TTL + drug<br />
**[[4o2b]] - bTUBA+bTUBB+stathmin-4 + TTL + drug<br />
Line 68: Line 88:
**[[5xiw]], [[5xke]], [[5xkf]], [[5xkg]], [[5xkh]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + drug<br />
**[[5xiw]], [[5xke]], [[5xkf]], [[5xkg]], [[5xkh]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + drug<br />
**[[5yl4]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + drug<br />
**[[5yl4]] – pTUBAB1 +pTUBBB2 +stathmin-4 + TTL + GDP + GTP + ATP derivative + drug<br />
**[[6o5n]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + imidazole derivative<br />
**[[5jqg]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative<br />
**[[6o61]], [[6o5m]] - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative<br />
**[[6nng]], [[6eg5]] - pTUBA+ pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative<br />
**[[6n47]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + pyrimidine derivative<br />
**[[5jcb]], [[5ca0]] - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + depolymerizer<br />
**[[5cb4]] – pTUBA + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
**[[5c8y]] – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent<br />
**[[5ezy]] - pTUBA+ bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + stabilizer<br />
**[[5zxh]] - pTUBA+ bTUBB (mutant) +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative<br />
**[[5z4u]], [[6agk]], [[5h7o]], [[5h74]] – pTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />
**[[5fnv]] – cTUBA + rTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent - chicken<br />
**[[5ca1]] – pTUBA + cTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor<br />


*α-tubulin + β-tubulin complex with kinesin
*α-tubulin + β-tubulin complex with kinesin
Line 76: Line 109:
**[[4ck5]], [[4ck6]], [[4ck7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
**[[4ck5]], [[4ck6]], [[4ck7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
**[[5mio]] - bTUBA+bTUBB+kinesin-like KIF2C motor domain<br />
**[[5mio]] - bTUBA+bTUBB+kinesin-like KIF2C motor domain<br />
**[[5hnw]], [[5hnx]], [[5hny]], [[5hnz]] – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + taxol<br />
**[[5hnw]], [[5hnx]], [[5hny]], [[5hnz]] – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + stabilizer<br />
**[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
**[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxy]] - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + taxol – Cryo EM<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxy]] - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + stabilizer – Cryo EM<br />
**[[4uxt]], [[4uy0]] - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + taxol – Cryo EM<br />
**[[4uxt]], [[4uy0]] - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + stabilizer – Cryo EM<br />
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
**[[4aqv]], [[4aqw ]]- bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
**[[4aqv]], [[4aqw ]]- bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
Line 88: Line 121:
**[[6bbn]] - bTUBA+bTUBB+kinesin-like KIF2A + DARPIN + AMPPNP + GDP + GTP<br />
**[[6bbn]] - bTUBA+bTUBB+kinesin-like KIF2A + DARPIN + AMPPNP + GDP + GTP<br />
**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
**[[5mm7]] - bTUBA1A+bTUBB +kinesin-4 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5mm4]] - bTUBA1A+bTUBB +kinesin-5 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5ogc]], [[5oam]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + stabilizer – Cryo EM<br />
**[[5ocu]] - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] - bTUBA1D+bTUBB2B+kinesin-5 motor domain + AMPPNP – Cryo EM<br />
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] - bTUBA1D+bTUBB2B+kinesin-5 motor domain + AMPPNP – Cryo EM<br />
**[[2hxf]], [[6b0c]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP - Cryo EM<br />
**[[2hxf]], [[6b0c]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP - Cryo EM<br />
Line 95: Line 132:
**[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br />
**[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br />
**[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br />
**[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br />
**[[6boi]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + taxol – Cryo EM<br />
**[[6tiw]] - pTUBA+pTUBB+kinesin-like KIF11 + G2P + quinoline derivative – Cryo EM<br />
**[[6b0l]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + AMPPNP + taxol – Cryo EM<br />
**[[6ta4]] - pTUBA+pTUBB+kinesin-like KIF11 + GTP + G2P + ANP – Cryo EM<br />
**[[6b0i]] - pTUBA+pTUBB+kinesin-like KLP10A + GTP + GDP + stabilizer – Cryo EM<br />
**[[6vpp]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP – Cryo EM<br />
**[[6vpo]] - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP + ANP – Cryo EM<br />
**[[6mlr]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ANP + stabilizer – Cryo EM<br />
**[[6mlq]] - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ADP + stabilizer – Cryo EM<br />
**[[6s8m]] - pTUBA+pTUBB+kinesin-like CUT7 + GTP + GDP + ANP – Cryo EM<br />
**[[6boi]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + stabilizer – Cryo EM<br />
**[[6b0l]] - pTUBA+pTUBB + kinesin-like KLP10A + GDP + GTP + AMPPNP + stabilizer – Cryo EM<br />
**[[4lnu]] - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain <br />
**[[4lnu]] - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain <br />
**[[5mlv]] - fyTUBA+ fyTUBB+kinesin-like CUT7 + GTP + GDP + ANP – fission yeast - Cryo EM<br />
**[[6u0h]] - TtTUBA+TUBB + GTP + GDP – ''Tetrahymena thermophila'' - Cryo EM<br />
**[[6u0u]], [[6u0t]] - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM<br />
**[[5o09]] - PdTUBA+TUBB +GDP + GTP + kinesin light chain - Cryo EM <br />
**[[5o09]] - PdTUBA+TUBB +GDP + GTP + kinesin light chain - Cryo EM <br />


*α-tubulin + β-tubulin other complexes
*α-tubulin + β-tubulin other complexes


**[[6s8l]], [[6s8k]] - hTUBA+hTUBB + ankyrin repeat protein + GDP + GTP + plinabulin<br />
**[[6rza]] - hTUBA+hTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM<br />
**[[6qvj]], [[6qus]] - hTUBA+hTUBB +GTP + GDP + stabilizer + CAMSAP1 – Cryo EM<br />
**[[6qve]] - hTUBA+hTUBB + GTP + GDP + stabilizer + protein – Cryo EM<br />
**[[6quy]] - hTUBA+hTUBB +GTP + GDP + stabilizer + CKK – Cryo EM<br />
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dynein<br />
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dynein<br />
**[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
**[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
**[[5itz]] - bTUBA+bTUBB + CENP-J + darpin + GTP + GDP + colchicine <br />
**[[5eib]] - bTUBA+bTUBB + CENP-J peptide + darpin + GTP + GDP<br />
**[[6kiq]], [[6kio]] - pTUBA+pTUBB + dynein heavy chain – Cryo EM<br />
**[[5nqu]], [[5nqt]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP<br />
**[[5nqu]], [[5nqt]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP<br />
**[[5nm5]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP + colchicine<br />
**[[5nm5]] - bTUBA+bTUBB + ankyrin repeat protein + GDP + GTP + colchicine<br />
**[[5m50]], [[5m54]], [[5m5c]] - bTUBA+bTUBB + calmodulin-regulated spectrin-associated protein + GDP + GTP - Cryo EM<br />
**[[5m50]], [[5m54]], [[5m5c]] - bTUBA+bTUBB + calmodulin-regulated spectrin-associated protein + GDP + GTP - Cryo EM<br />
**[[3j6p]] - pTUBA+pTUBB +GTP + GDP + taxol + dynein heavy chain – Cryo EM<br />
**[[3j6p]], [[6rzb]] - pTUBA+pTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM<br />
**[[3j6g]] - pTUBA+pTUBB +GTP + GDP + taxol – Cryo EM <br />
**[[3j6g]] - pTUBA+pTUBB +GTP + GDP + taxol – Cryo EM <br />
**[[6cvj]], [[6cvn]] - pTUBA+pTUBB + GTP + GDP + tau protein – Cryo EM <br />
**[[6cvj]], [[6cvn]] - pTUBA+pTUBB + GTP + GDP + tau protein – Cryo EM <br />
**[[5kmg]] - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM <br />
**[[5kmg]] - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM <br />
**[[6mzg]], [[6mzf]], [[6mze]] - pTUBA+pTUBB + STU2P + darpin + GTP + GDP  <br />
**[[5syg]], [[5syf]], [[5sye]], [[5syc]] - pTUBA+pTUBB + STU2P + stabilizer + GTP + GDP  <br />                         
**[[6gx7]] - sTUBA+sTUBB + alpharep + low calcium response + GTP<br />
**[[6gwd]], [[6gwc]] - sTUBA+sTUBB + alpharep + GTP + GDP<br />
**[[6bjc]] - pTUBA+pTUBB + targeting protein for Xklp2 + GTP + GMPCPP – Cryo EM <br />
**[[6bjc]] - pTUBA+pTUBB + targeting protein for Xklp2 + GTP + GMPCPP – Cryo EM <br />
**[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
**[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
**[[4ffb]], [[4u3j]] - yTUBA+TUBB (mutant) + protein STU2 <br />
**[[4ffb]], [[4u3j]] - yTUBA+TUBB (mutant) + protein STU2 <br />
**[[5mjs]] - fyTUBA+ fyTUBB + MAL3 + GTP + GDP + ANP - Cryo EM<br />


*γ-tubulin
*γ-tubulin


**[[6v5v]] – hTUBG1 – Cryo EM<br />
**[[3cb2]] – hTUBG1+GDP<br />
**[[3cb2]] – hTUBG1+GDP<br />
**[[1z5v]] - hTUBG1+GTPgS<br />
**[[1z5v]] - hTUBG1+GTPgS<br />
**[[1z5w]] - hTUBG1+GTP<br />
**[[1z5w]] - hTUBG1+GTP<br />
**[[6v6b]] – hTUBG2 + TUBG3 – Cryo EM<br />
**[[3rip]] – hTUBG4<br />
**[[3rip]] – hTUBG4<br />
**[[6v69]] – hTUBG4 + TUBG5 – Cryo EM<br />
**[[6v6c]] – hTUBG6 – Cryo EM<br />


}}
}}

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman
Retrieved from "https://proteopedia.openfox.io/w/Tubulin"