2krr: Difference between revisions
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==Solution structure of the RBD1,2 domains from human nucleolin== | ==Solution structure of the RBD1,2 domains from human nucleolin== | ||
<StructureSection load='2krr' size='340' side='right' caption='[[2krr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2krr' size='340' side='right'caption='[[2krr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2krr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KRR FirstGlance]. <br> | <table><tr><td colspan='2'>[[2krr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KRR FirstGlance]. <br> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Arumugam, N]] | [[Category: Arumugam, N]] | ||
[[Category: Bates, P J]] | [[Category: Bates, P J]] | ||
Revision as of 12:43, 26 February 2020
Solution structure of the RBD1,2 domains from human nucleolinSolution structure of the RBD1,2 domains from human nucleolin
Structural highlights
Function[NUCL_HUMAN] Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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